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Page 1
Cancer associated fibroblasts and tumor growth: focus on multiple myeloma.
De Veirman K, Rao L, De Bruyne E, Menu E, Van Valckenborgh E, Van Riet I, Frassanito MA, Di Marzo L, Vacca A, Vanderkerken K. De Veirman K, et al. Among authors: vacca a. Cancers (Basel). 2014 Jun 27;6(3):1363-81. doi: 10.3390/cancers6031363. Cancers (Basel). 2014. PMID: 24978438 Free PMC article.
Pentraxin 3 (PTX3) inhibits plasma cell/stromal cell cross-talk in the bone marrow of multiple myeloma patients.
Basile A, Moschetta M, Ditonno P, Ria R, Marech I, De Luisi A, Berardi S, Frassanito MA, Angelucci E, Derudas D, Specchia G, Curci P, Pavone V, Rossini B, Ribatti D, Bottazzi B, Mantovani A, Presta M, Dammacco F, Vacca A. Basile A, et al. Among authors: vacca a. J Pathol. 2013 Jan;229(1):87-98. doi: 10.1002/path.4081. Epub 2012 Oct 1. J Pathol. 2013. PMID: 22847671 Free article.
Novel targeting of phospho-cMET overcomes drug resistance and induces antitumor activity in multiple myeloma.
Moschetta M, Basile A, Ferrucci A, Frassanito MA, Rao L, Ria R, Solimando AG, Giuliani N, Boccarelli A, Fumarola F, Coluccia M, Rossini B, Ruggieri S, Nico B, Maiorano E, Ribatti D, Roccaro AM, Vacca A. Moschetta M, et al. Among authors: vacca a. Clin Cancer Res. 2013 Aug 15;19(16):4371-82. doi: 10.1158/1078-0432.CCR-13-0039. Epub 2013 Jun 26. Clin Cancer Res. 2013. PMID: 23804425
HIF-1α of bone marrow endothelial cells implies relapse and drug resistance in patients with multiple myeloma and may act as a therapeutic target.
Ria R, Catacchio I, Berardi S, De Luisi A, Caivano A, Piccoli C, Ruggieri V, Frassanito MA, Ribatti D, Nico B, Annese T, Ruggieri S, Guarini A, Minoia C, Ditonno P, Angelucci E, Derudas D, Moschetta M, Dammacco F, Vacca A. Ria R, et al. Among authors: vacca a. Clin Cancer Res. 2014 Feb 15;20(4):847-58. doi: 10.1158/1078-0432.CCR-13-1950. Epub 2013 Dec 2. Clin Cancer Res. 2014. PMID: 24297864
Macrophages in multiple myeloma.
Ribatti D, Moschetta M, Vacca A. Ribatti D, et al. Among authors: vacca a. Immunol Lett. 2014 Oct;161(2):241-4. doi: 10.1016/j.imlet.2013.12.010. Epub 2013 Dec 24. Immunol Lett. 2014. PMID: 24370642 Review.
Stimulation of invariant natural killer T cells by α-Galactosylceramide activates the JAK-STAT pathway in endothelial cells and reduces angiogenesis in the 5T33 multiple myeloma model.
Nur H, Rao L, Frassanito MA, De Raeve H, Ribatti D, Mfopou JK, Van Valckenborgh E, De Bruyne E, Vacca A, Vanderkerken K, Menu E. Nur H, et al. Among authors: vacca a. Br J Haematol. 2014 Dec;167(5):651-63. doi: 10.1111/bjh.13092. Epub 2014 Aug 21. Br J Haematol. 2014. PMID: 25142285 Free article.
A HGF/cMET autocrine loop is operative in multiple myeloma bone marrow endothelial cells and may represent a novel therapeutic target.
Ferrucci A, Moschetta M, Frassanito MA, Berardi S, Catacchio I, Ria R, Racanelli V, Caivano A, Solimando AG, Vergara D, Maffia M, Latorre D, Rizzello A, Zito A, Ditonno P, Maiorano E, Ribatti D, Vacca A. Ferrucci A, et al. Among authors: vacca a. Clin Cancer Res. 2014 Nov 15;20(22):5796-807. doi: 10.1158/1078-0432.CCR-14-0847. Epub 2014 Sep 11. Clin Cancer Res. 2014. PMID: 25212607
888 results