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A Hydrogel Dressing Comprised of Silk Fibroin, Ag Nanoparticles, and Reduced Graphene Oxide for NIR Photothermal-Enhanced Antibacterial Efficiency and Skin Regeneration.
Yan S, Xu S, Wang Y, You J, Guo C, Wu X. Yan S, et al. Adv Healthc Mater. 2024 May 3:e2400884. doi: 10.1002/adhm.202400884. Online ahead of print. Adv Healthc Mater. 2024. PMID: 38701326
In this study, a multifunctional wound dressing (SF/Ag@rGO hydrogel) is developed to promote the healing of infected skin wounds by combining the inherent antibacterial activity of Ag nanoparticles (NPs) with near-infrared (NIR)-assisted antibacterial therapy. Initially, L-asc
In this study, a multifunctional wound dressing (SF/Ag@rGO hydrogel) is developed to promote the healing of infected skin wounds by combinin …
Noble Metal-Free Light-Driven Hydrogen Evolution Catalysis in Polyampholytic Hydrogel Networks.
Ceper T, Costabel D, Kowalczyk D, Peneva K, Schacher FH. Ceper T, et al. ACS Appl Mater Interfaces. 2024 May 3. doi: 10.1021/acsami.4c04045. Online ahead of print. ACS Appl Mater Interfaces. 2024. PMID: 38700504
The resulting material exhibits sustained visible-light-driven H(2) evolution in aqueous ascorbic acid solution, even at rather low loadings of photosensitizer (0.4%) and catalyst (120 ppm). ...
The resulting material exhibits sustained visible-light-driven H(2) evolution in aqueous ascorbic acid solution, even at rathe …
Ascorbic acid metabolism and functions.
Conklin PL, Foyer CH, Hancock RD, Ishikawa T, Smirnoff N. Conklin PL, et al. J Exp Bot. 2024 May 3;75(9):2599-2603. doi: 10.1093/jxb/erae143. J Exp Bot. 2024. PMID: 38699987
Targeted screening of multiple anti-inflammatory components from Chrysanthemi indici Flos by ligand fishing with affinity UF-LC/MS.
Huang C, Xiong X, Zhang D, Ruan Q, Jiang J, Wang F, Chen G, Cheng L. Huang C, et al. Front Pharmacol. 2024 Apr 16;15:1272087. doi: 10.3389/fphar.2024.1272087. eCollection 2024. Front Pharmacol. 2024. PMID: 38694923 Free PMC article.

Besides, CIFE strongly inhibited the COX-2 and hyaluronidase (HAase) with the IC50 values of 1.06 0.01 mug/mL and 12.22 0.39 mug/mL, indicating higher inhibitory effect than positive control of aspirin of 6.33 0.05 mug/mL (p < 0.01), and comparable inhibitory effect with indom

Besides, CIFE strongly inhibited the COX-2 and hyaluronidase (HAase) with the IC50 values of 1.06 0.01 mug/mL and 12.22 0.39 mug/mL, indicat …
Phenylethanoid glycosides from Michelia champaca leaves.
Liu M, Tan H, Xie H. Liu M, et al. Phytochemistry. 2024 Apr 29:114118. doi: 10.1016/j.phytochem.2024.114118. Online ahead of print. Phytochemistry. 2024. PMID: 38692344
Twenty-one PhGs exhibited more potent DPPH radical scavenging activity and FRAP than l-ascorbic acid (l-AA), and twenty-two PhGs showed better ABTS radical cation scavenging activity than l-AA. ...
Twenty-one PhGs exhibited more potent DPPH radical scavenging activity and FRAP than l-ascorbic acid (l-AA), and twenty-two Ph …
Molecular dynamics simulations of choline chloride and ascorbic acid deep eutectic solvents: Investigation of structural and dynamics properties.
Cheng K, Xu X, Song J, Chen Y, Kan Z, Li C. Cheng K, et al. J Mol Graph Model. 2024 Apr 26;130:108784. doi: 10.1016/j.jmgm.2024.108784. Online ahead of print. J Mol Graph Model. 2024. PMID: 38692127
Deep eutectic solvents (DESs) composed of choline chloride (ChCl) and ascorbic acid (AA) were investigated using the molecular dynamics (MD) simulations. ...
Deep eutectic solvents (DESs) composed of choline chloride (ChCl) and ascorbic acid (AA) were investigated using the molecular …
NOX2 and NOX4 expression in monocytes and macrophages-extracellular vesicles in signalling and therapeutics.
Rathi D, Rossi C, Pospíšil P, Ramalingam Manoharan R, Talarico L, Magnani A, Prasad A. Rathi D, et al. Front Cell Dev Biol. 2024 Apr 16;12:1342227. doi: 10.3389/fcell.2024.1342227. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 38690564 Free PMC article.
The results showed that the exogenous addition of differentiation agents (either phorbol 12-myristate 13-acetate (PMA) or ascorbic acid) or the supplementation of EVs used in the study did not cause any stress leading to alterations in cell proliferation and viabili …
The results showed that the exogenous addition of differentiation agents (either phorbol 12-myristate 13-acetate (PMA) or ascorbic
A clinic-pathological research explored the significance of ascorbic acid and iron levels in serum and saliva in premalignant disorder patients at Kanpur, Uttar Pradesh.
Sachdev R, Garg K, Mehrotra V, Shwetam S, Singh P, Srivastava A. Sachdev R, et al. Natl J Maxillofac Surg. 2024 Jan-Apr;15(1):131-135. doi: 10.4103/njms.njms_470_21. Epub 2024 Mar 19. Natl J Maxillofac Surg. 2024. PMID: 38690244 Free PMC article.
AIMS: This study aimed to investigate the significance of ascorbic acid and iron levels in serum and saliva in patients with premalignant disorder (OSMF) and to correlate variations in ascorbic acid and iron levels with histopathological grading. ...CO …
AIMS: This study aimed to investigate the significance of ascorbic acid and iron levels in serum and saliva in patients with p …
BN-BacArena: Bayesian network extension of BacArena for the dynamic simulation of microbial communities.
Blasco T, Balzerani F, Valcárcel LV, Larrañaga P, Bielza C, Francino MP, Rufián-Henares JÁ, Planes FJ, Pérez-Burillo S. Blasco T, et al. Bioinformatics. 2024 Apr 30:btae266. doi: 10.1093/bioinformatics/btae266. Online ahead of print. Bioinformatics. 2024. PMID: 38688585
Using in vitro experiments, 16S rRNA gene sequencing data and nutritional composition of 55 foods, the output Bayesian network showed 23 significant nutrient-bacteria interactions, suggesting the importance of compounds such as polyols, ascorbic acid, polyphenols an …
Using in vitro experiments, 16S rRNA gene sequencing data and nutritional composition of 55 foods, the output Bayesian network showed 23 sig …
Design, synthesis, and biological evaluation of novel 2,3-Di-O-Aryl/Alkyl sulfonate derivatives of l-ascorbic acid: Efficient access to novel anticancer agents via in vitro screening, tubulin polymerization inhibition, molecular docking study and ADME predictions.
Deshmukh SR, Nalkar AS, Sarkate AP, Tiwari SV, Lokwani DK, Thopate SR. Deshmukh SR, et al. Bioorg Chem. 2024 Apr 26;147:107402. doi: 10.1016/j.bioorg.2024.107402. Online ahead of print. Bioorg Chem. 2024. PMID: 38688199
A series of novel l-ascorbic acid derivatives bearing aryl and alkyl sulfonate substituents were synthesized and characterized. ...In-silico ADMET predictions indicated favourable drug-like properties, with 2b exhibiting the highest binding affinity. These sulfonate …
A series of novel l-ascorbic acid derivatives bearing aryl and alkyl sulfonate substituents were synthesized and characterized …
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