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VE607 stabilizes SARS-CoV-2 Spike in the "RBD-up" conformation and inhibits viral entry.
Ding S, Ullah I, Gong SY, Grover JR, Mohammadi M, Chen Y, Vézina D, Beaudoin-Bussières G, Verma VT, Goyette G, Gaudette F, Richard J, Yang D, Smith AB 3rd, Pazgier M, Côté M, Abrams C, Kumar P, Mothes W, Uchil PD, Finzi A, Baron C. Ding S, et al. Among authors: vezina d. iScience. 2022 Jul 15;25(7):104528. doi: 10.1016/j.isci.2022.104528. Epub 2022 Jun 3. iScience. 2022. PMID: 35677392 Free PMC article.
Identification of HIV gp41-specific antibodies that mediate killing of infected cells.
Williams KL, Stumpf M, Naiman NE, Ding S, Garrett M, Gobillot T, Vézina D, Dusenbury K, Ramadoss NS, Basom R, Kim PS, Finzi A, Overbaugh J. Williams KL, et al. Among authors: vezina d. PLoS Pathog. 2019 Feb 19;15(2):e1007572. doi: 10.1371/journal.ppat.1007572. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30779811 Free PMC article.
A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity.
Ding S, Grenier MC, Tolbert WD, Vézina D, Sherburn R, Richard J, Prévost J, Chapleau JP, Gendron-Lepage G, Medjahed H, Abrams C, Sodroski J, Pazgier M, Smith AB 3rd, Finzi A. Ding S, et al. Among authors: vezina d. J Virol. 2019 Nov 26;93(24):e01325-19. doi: 10.1128/JVI.01325-19. Print 2019 Dec 15. J Virol. 2019. PMID: 31554684 Free PMC article.
Optimization of Small Molecules That Sensitize HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity.
Grenier MC, Ding S, Vézina D, Chapleau JP, Tolbert WD, Sherburn R, Schön A, Somisetti S, Abrams CF, Pazgier M, Finzi A, Smith AB 3rd. Grenier MC, et al. Among authors: vezina d. ACS Med Chem Lett. 2019 Nov 15;11(3):371-378. doi: 10.1021/acsmedchemlett.9b00445. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184972 Free PMC article.
Stabilizing the HIV-1 envelope glycoprotein State 2A conformation.
Vézina D, Gong SY, Tolbert WD, Ding S, Nguyen D, Richard J, Gendron-Lepage G, Melillo B 3rd, Smith AB, Pazgier M, Finzi A. Vézina D, et al. J Virol. 2021 Mar 1;95(5):e01620-20. doi: 10.1128/JVI.01620-20. Epub 2020 Dec 9. J Virol. 2021. PMID: 33298541 Free PMC article.
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: vezina d. Cell Host Microbe. 2021 Jul 14;29(7):1137-1150.e6. doi: 10.1016/j.chom.2021.06.001. Epub 2021 Jun 4. Cell Host Microbe. 2021. PMID: 34133950 Free PMC article.
Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells.
Richard J, Nguyen DN, Tolbert WD, Gasser R, Ding S, Vézina D, Yu Gong S, Prévost J, Gendron-Lepage G, Medjahed H, Gottumukkala S, Finzi A, Pazgier M. Richard J, et al. Among authors: vezina d. mBio. 2021 Oct 26;12(5):e0140521. doi: 10.1128/mBio.01405-21. Epub 2021 Sep 28. mBio. 2021. PMID: 34579568 Free PMC article.
Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses.
Tauzin A, Gong SY, Beaudoin-Bussières G, Vézina D, Gasser R, Nault L, Marchitto L, Benlarbi M, Chatterjee D, Nayrac M, Laumaea A, Prévost J, Boutin M, Sannier G, Nicolas A, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Bo Y, Perreault J, Gokool L, Morrisseau C, Arlotto P, Bazin R, Dubé M, De Serres G, Brousseau N, Richard J, Rovito R, Côté M, Tremblay C, Marchetti GC, Duerr R, Martel-Laferrière V, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: vezina d. Cell Host Microbe. 2022 Jan 12;30(1):97-109.e5. doi: 10.1016/j.chom.2021.12.004. Epub 2021 Dec 3. Cell Host Microbe. 2022. PMID: 34953513 Free PMC article.
45 results