Välitalo PA - Search Results

1

Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach.

Yamamoto Y, Välitalo PA, Wong YC, Huntjens DR, Proost JH, Vermeulen A, Krauwinkel W, Beukers MW, Kokki H, Kokki M, Danhof M, van Hasselt JGC, de Lange ECM. Yamamoto Y, et al. Among authors: valitalo pa. Eur J Pharm Sci. 2018 Jan 15;112:168-179. doi: 10.1016/j.ejps.2017.11.011. Epub 2017 Nov 11. Eur J Pharm Sci. 2018. PMID: 29133240

2

Plasma and cerebrospinal fluid pharmacokinetics of flurbiprofen in children.

Kumpulainen E, Välitalo P, Kokki M, Lehtonen M, Hooker A, Ranta VP, Kokki H. Kumpulainen E, et al. Br J Clin Pharmacol. 2010 Oct;70(4):557-66. doi: 10.1111/j.1365-2125.2010.03720.x. Br J Clin Pharmacol. 2010. PMID: 20840447 Free PMC article.

3

Plasma and cerebrospinal fluid pharmacokinetics of naproxen in children.

Välitalo P, Kumpulainen E, Manner M, Kokki M, Lehtonen M, Hooker AC, Ranta VP, Kokki H. Välitalo P, et al. J Clin Pharmacol. 2012 Oct;52(10):1516-26. doi: 10.1177/0091270011418658. Epub 2011 Nov 8. J Clin Pharmacol. 2012. PMID: 22067196

4

Intravenous oxycodone for pain relief in the first stage of labour--maternal pharmacokinetics and neonatal exposure.

Kokki M, Franco MG, Raatikainen K, Välitalo P, Sankilampi U, Heinonen S, Neuvonen PJ, Kokki H. Kokki M, et al. Basic Clin Pharmacol Toxicol. 2012 Sep;111(3):182-8. doi: 10.1111/j.1742-7843.2012.00884.x. Epub 2012 Apr 21. Basic Clin Pharmacol Toxicol. 2012. PMID: 22448718 Free article. Clinical Trial.

5

Absorption of different oral dosage forms of oxycodone in the elderly: a cross-over clinical trial in patients undergoing cystoscopy.

Kokki M, Välitalo P, Rasanen I, Aaltomaa S, Ojanperä I, Eskelinen M, Kokki H. Kokki M, et al. Eur J Clin Pharmacol. 2012 Oct;68(10):1357-63. doi: 10.1007/s00228-012-1267-9. Epub 2012 Mar 27. Eur J Clin Pharmacol. 2012. PMID: 22451244 Clinical Trial.

6

Central nervous system penetration of oxycodone after intravenous and epidural administration.

Kokki M, Välitalo P, Kuusisto M, Ranta VP, Raatikainen K, Hautajärvi H, Kokki H. Kokki M, et al. Br J Anaesth. 2014 Jan;112(1):133-40. doi: 10.1093/bja/aet337. Epub 2013 Oct 16. Br J Anaesth. 2014. PMID: 24131664 Free article. Clinical Trial.

7

Population pharmacometrics in support of analgesics studies.

Välitalo P, Ranta VP, Hooker AC, Kokki M, Kokki H. Välitalo P, et al. Acta Anaesthesiol Scand. 2014 Feb;58(2):143-56. doi: 10.1111/aas.12253. Epub 2014 Jan 2. Acta Anaesthesiol Scand. 2014. PMID: 24383522 Review.

8

Structure-Based Prediction of Anti-infective Drug Concentrations in the Human Lung Epithelial Lining Fluid.

Välitalo PA, Griffioen K, Rizk ML, Visser SA, Danhof M, Rao G, van der Graaf PH, van Hasselt JG. Välitalo PA, et al. Pharm Res. 2016 Apr;33(4):856-67. doi: 10.1007/s11095-015-1832-x. Epub 2015 Dec 1. Pharm Res. 2016. PMID: 26626793

9

Semiphysiologically based pharmacokinetic model for midazolam and CYP3A mediated metabolite 1-OH-midazolam in morbidly obese and weight loss surgery patients.

Brill MJ, Välitalo PA, Darwich AS, van Ramshorst B, van Dongen HP, Rostami-Hodjegan A, Danhof M, Knibbe CA. Brill MJ, et al. Among authors: valitalo pa. CPT Pharmacometrics Syst Pharmacol. 2016 Jan;5(1):20-30. doi: 10.1002/psp4.12048. Epub 2015 Dec 18. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 26844012 Free PMC article.

10

Allometric Scaling of Clearance in Paediatric Patients: When Does the Magic of 0.75 Fade?

Calvier EA, Krekels EH, Välitalo PA, Rostami-Hodjegan A, Tibboel D, Danhof M, Knibbe CA. Calvier EA, et al. Among authors: valitalo pa. Clin Pharmacokinet. 2017 Mar;56(3):273-285. doi: 10.1007/s40262-016-0436-x. Clin Pharmacokinet. 2017. PMID: 27510367 Free PMC article.

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