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Serum proteomes distinguish children developing type 1 diabetes in a cohort with HLA-conferred susceptibility.
Moulder R, Bhosale SD, Erkkilä T, Laajala E, Salmi J, Nguyen EV, Kallionpää H, Mykkänen J, Vähä-Mäkilä M, Hyöty H, Veijola R, Ilonen J, Simell T, Toppari J, Knip M, Goodlett DR, Lähdesmäki H, Simell O, Lahesmaa R. Moulder R, et al. Diabetes. 2015 Jun;64(6):2265-78. doi: 10.2337/db14-0983. Epub 2015 Jan 23. Diabetes. 2015. PMID: 25616278
Reduced β-cell function in early preclinical type 1 diabetes.
Koskinen MK, Helminen O, Matomäki J, Aspholm S, Mykkänen J, Mäkinen M, Simell V, Vähä-Mäkilä M, Simell T, Ilonen J, Knip M, Veijola R, Toppari J, Simell O. Koskinen MK, et al. Eur J Endocrinol. 2016 Mar;174(3):251-9. doi: 10.1530/EJE-15-0674. Epub 2015 Nov 30. Eur J Endocrinol. 2016. PMID: 26620391 Free PMC article.
Permutation-based significance analysis reduces the type 1 error rate in bisulphite sequencing data analysis of human umbilical cord blood samples.
Laajala E, Halla-Aho V, Grönroos T, Kalim UU, Vähä-Mäkilä M, Nurmio M, Kallionpää H, Lietzén N, Mykkänen J, Rasool O, Toppari J, Orešič M, Knip M, Lund R, Lahesmaa R, Lähdesmäki H. Laajala E, et al. Epigenetics. 2022 Dec;17(12):1608-1627. doi: 10.1080/15592294.2022.2044127. Epub 2022 Mar 4. Epigenetics. 2022. PMID: 35246015 Free PMC article.
Umbilical cord blood DNA methylation in children who later develop type 1 diabetes.
Laajala E, Kalim UU, Grönroos T, Rasool O, Halla-Aho V, Konki M, Kattelus R, Mykkänen J, Nurmio M, Vähä-Mäkilä M, Kallionpää H, Lietzén N, Ghimire BR, Laiho A, Hyöty H, Elo LL, Ilonen J, Knip M, Lund RJ, Orešič M, Veijola R, Lähdesmäki H, Toppari J, Lahesmaa R. Laajala E, et al. Among authors: vaha makila m. Diabetologia. 2022 Sep;65(9):1534-1540. doi: 10.1007/s00125-022-05726-1. Epub 2022 Jun 18. Diabetologia. 2022. PMID: 35716175 Free PMC article.
Natural Development of Antibodies against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Protein Antigens during the First 13 Years of Life.
Borges IC, Andrade DC, Cardoso MR, Toppari J, Vähä-Mäkilä M, Ilonen J, Knip M, Hyöty H, Veijola R, Simell O, Jartti T, Käyhty H, Ruuskanen O, Nascimento-Carvalho CM. Borges IC, et al. Clin Vaccine Immunol. 2016 Nov 4;23(11):878-883. doi: 10.1128/CVI.00341-16. Print 2016 Nov. Clin Vaccine Immunol. 2016. PMID: 27581439 Free PMC article.
Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity.
Norris JM, Lee HS, Frederiksen B, Erlund I, Uusitalo U, Yang J, Lernmark Å, Simell O, Toppari J, Rewers M, Ziegler AG, She JX, Onengut-Gumuscu S, Chen WM, Rich SS, Sundvall J, Akolkar B, Krischer J, Virtanen SM, Hagopian W; TEDDY Study Group. Norris JM, et al. Diabetes. 2018 Jan;67(1):146-154. doi: 10.2337/db17-0802. Epub 2017 Oct 23. Diabetes. 2018. PMID: 29061729 Free PMC article.
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