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Reducing acetylated tau is neuroprotective in brain injury.
Shin MK, Vázquez-Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón-Pérez CJ, Barker S, Miller E, Franke K, Noterman MF, Seth D, Allen RS, Motz CT, Rao SR, Skelton LA, Pardue MT, Fliesler SJ, Wang C, Tracy TE, Gan L, Liebl DJ, Savarraj JPJ, Torres GL, Ahnstedt H, McCullough LD, Kitagawa RS, Choi HA, Zhang P, Hou Y, Chiang CW, Li L, Ortiz F, Kilgore JA, Williams NS, Whitehair VC, Gefen T, Flanagan ME, Stamler JS, Jain MK, Kraus A, Cheng F, Reynolds JD, Pieper AA. Shin MK, et al. Among authors: vazquez rosa e. Cell. 2021 May 13;184(10):2715-2732.e23. doi: 10.1016/j.cell.2021.03.032. Epub 2021 Apr 13. Cell. 2021. PMID: 33852912 Free PMC article.
Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease.
De Jesús-Cortés H, Miller AD, Britt JK, DeMarco AJ, De Jesús-Cortés M, Stuebing E, Naidoo J, Vázquez-Rosa E, Morlock L, Williams NS, Ready JM, Narayanan NS, Pieper AA. De Jesús-Cortés H, et al. NPJ Parkinsons Dis. 2015;1:15010-. doi: 10.1038/npjparkd.2015.10. Epub 2015 May 21. NPJ Parkinsons Dis. 2015. PMID: 27158662 Free PMC article.
Neuroprotective efficacy of P7C3 compounds in primate hippocampus.
Bauman MD, Schumann CM, Carlson EL, Taylor SL, Vázquez-Rosa E, Cintrón-Pérez CJ, Shin MK, Williams NS, Pieper AA. Bauman MD, et al. Transl Psychiatry. 2018 Sep 26;8(1):202. doi: 10.1038/s41398-018-0244-1. Transl Psychiatry. 2018. PMID: 30258178 Free PMC article.
Identification of chronic brain protein changes and protein targets of serum auto-antibodies after blast-mediated traumatic brain injury.
Harper MM, Rudd D, Meyer KJ, Kanthasamy AG, Anantharam V, Pieper AA, Vázquez-Rosa E, Shin MK, Chaubey K, Koh Y, Evans LP, Bassuk AG, Anderson MG, Dutca L, Kudva IT, John M. Harper MM, et al. Among authors: vazquez rosa e. Heliyon. 2020 Feb 17;6(2):e03374. doi: 10.1016/j.heliyon.2020.e03374. eCollection 2020 Feb. Heliyon. 2020. PMID: 32099918 Free PMC article.
P7C3-A20 treatment one year after TBI in mice repairs the blood-brain barrier, arrests chronic neurodegeneration, and restores cognition.
Vázquez-Rosa E, Shin MK, Dhar M, Chaubey K, Cintrón-Pérez CJ, Tang X, Liao X, Miller E, Koh Y, Barker S, Franke K, Crosby DR, Schroeder R, Emery J, Yin TC, Fujioka H, Reynolds JD, Harper MM, Jain MK, Pieper AA. Vázquez-Rosa E, et al. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27667-27675. doi: 10.1073/pnas.2010430117. Epub 2020 Oct 21. Proc Natl Acad Sci U S A. 2020. PMID: 33087571 Free PMC article.
19 results