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The anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler.
Pardo-Andreu GL, Nuñez-Figueredo Y, Tudella VG, Cuesta-Rubio O, Rodrigues FP, Pestana CR, Uyemura SA, Leopoldino AM, Alberici LC, Curti C. Pardo-Andreu GL, et al. Among authors: uyemura sa. Mitochondrion. 2011 Mar;11(2):255-63. doi: 10.1016/j.mito.2010.10.008. Epub 2010 Oct 31. Mitochondrion. 2011. PMID: 21044702
The anti-cancer agent guttiferone-A permeabilizes mitochondrial membrane: ensuing energetic and oxidative stress implications.
Pardo-Andreu GL, Nuñez-Figueredo Y, Tudella VG, Cuesta-Rubio O, Rodrigues FP, Pestana CR, Uyemura SA, Leopoldino AM, Alberici LC, Curti C. Pardo-Andreu GL, et al. Among authors: uyemura sa. Toxicol Appl Pharmacol. 2011 Jun 15;253(3):282-9. doi: 10.1016/j.taap.2011.04.011. Epub 2011 Apr 27. Toxicol Appl Pharmacol. 2011. PMID: 21549140 Free article.
C-Phycocyanin protects SH-SY5Y cells from oxidative injury, rat retina from transient ischemia and rat brain mitochondria from Ca2+/phosphate-induced impairment.
Marín-Prida J, Pentón-Rol G, Rodrigues FP, Alberici LC, Stringhetta K, Leopoldino AM, Naal Z, Polizello AC, Llópiz-Arzuaga A, Rosa MN, Liberato JL, Santos WF, Uyemura SA, Pentón-Arias E, Curti C, Pardo-Andreu GL. Marín-Prida J, et al. Among authors: uyemura sa. Brain Res Bull. 2012 Dec 1;89(5-6):159-67. doi: 10.1016/j.brainresbull.2012.08.011. Epub 2012 Sep 7. Brain Res Bull. 2012. PMID: 22982368 Free article.
The cytotoxic effects of VE-3N, a novel 1,4-dihydropyridine derivative, involve the mitochondrial bioenergetic disruption via uncoupling mechanisms.
Marín-Prida J, Pardo Andreu GL, Rossignoli CP, Durruthy MG, Rodríguez EO, Reyes YV, Acosta RF, Uyemura SA, Alberici LC. Marín-Prida J, et al. Among authors: uyemura sa. Toxicol In Vitro. 2017 Aug;42:21-30. doi: 10.1016/j.tiv.2017.03.011. Epub 2017 Mar 29. Toxicol In Vitro. 2017. PMID: 28363597 Free article.
106 results