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Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles.
Pavan C, Santalucia R, Leinardi R, Fabbiani M, Yakoub Y, Uwambayinema F, Ugliengo P, Tomatis M, Martra G, Turci F, Lison D, Fubini B. Pavan C, et al. Among authors: uwambayinema f. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):27836-27846. doi: 10.1073/pnas.2008006117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097669 Free PMC article.
The D prostanoid receptor agonist BW245C [(4S)-(3-[(3R,S)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxo)-4-imidazolidineheptanoic acid] inhibits fibroblast proliferation and bleomycin-induced lung fibrosis in mice.
van den Brule S, Wallemme L, Uwambayinema F, Huaux F, Lison D. van den Brule S, et al. Among authors: uwambayinema f. J Pharmacol Exp Ther. 2010 Nov;335(2):472-9. doi: 10.1124/jpet.110.169250. Epub 2010 Aug 18. J Pharmacol Exp Ther. 2010. PMID: 20719937
Critical role of aquaporins in interleukin 1β (IL-1β)-induced inflammation.
Rabolli V, Wallemme L, Lo Re S, Uwambayinema F, Palmai-Pallag M, Thomassen L, Tyteca D, Octave JN, Marbaix E, Lison D, Devuyst O, Huaux F. Rabolli V, et al. Among authors: uwambayinema f. J Biol Chem. 2014 May 16;289(20):13937-47. doi: 10.1074/jbc.M113.534594. Epub 2014 Apr 3. J Biol Chem. 2014. PMID: 24700466 Free PMC article.
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