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The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination.
Wimmers F, Donato M, Kuo A, Ashuach T, Gupta S, Li C, Dvorak M, Foecke MH, Chang SE, Hagan T, De Jong SE, Maecker HT, van der Most R, Cheung P, Cortese M, Bosinger SE, Davis M, Rouphael N, Subramaniam S, Yosef N, Utz PJ, Khatri P, Pulendran B. Wimmers F, et al. Among authors: utz pj. Cell. 2021 Jul 22;184(15):3915-3935.e21. doi: 10.1016/j.cell.2021.05.039. Epub 2021 Jun 25. Cell. 2021. PMID: 34174187 Free PMC article. Clinical Trial.
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling.
Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, Cheung P, Espejo A, Zee BM, Liu CL, Tangsombatvisit S, Tennen RI, Kuo AY, Tanjing S, Cheung R, Chua KF, Utz PJ, Shi X, Prinjha RK, Lee K, Garcia BA, Bedford MT, Tarakhovsky A, Cheng X, Gozani O. Levy D, et al. Among authors: utz pj. Nat Immunol. 2011 Jan;12(1):29-36. doi: 10.1038/ni.1968. Epub 2010 Dec 5. Nat Immunol. 2011. PMID: 21131967 Free PMC article.
New tools for classification and monitoring of autoimmune diseases.
Maecker HT, Lindstrom TM, Robinson WH, Utz PJ, Hale M, Boyd SD, Shen-Orr SS, Fathman CG. Maecker HT, et al. Among authors: utz pj. Nat Rev Rheumatol. 2012 May 31;8(6):317-28. doi: 10.1038/nrrheum.2012.66. Nat Rev Rheumatol. 2012. PMID: 22647780 Free PMC article. Review.
Apoptosis and other immune biomarkers predict influenza vaccine responsiveness.
Furman D, Jojic V, Kidd B, Shen-Orr S, Price J, Jarrell J, Tse T, Huang H, Lund P, Maecker HT, Utz PJ, Dekker CL, Koller D, Davis MM. Furman D, et al. Among authors: utz pj. Mol Syst Biol. 2013 Apr 16;9:659. doi: 10.1038/msb.2013.15. Mol Syst Biol. 2013. PMID: 23591775 Free PMC article.
Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus.
O'Gorman WE, Hsieh EW, Savig ES, Gherardini PF, Hernandez JD, Hansmann L, Balboni IM, Utz PJ, Bendall SC, Fantl WJ, Lewis DB, Nolan GP, Davis MM. O'Gorman WE, et al. Among authors: utz pj. J Allergy Clin Immunol. 2015 Nov;136(5):1326-36. doi: 10.1016/j.jaci.2015.04.008. Epub 2015 May 30. J Allergy Clin Immunol. 2015. PMID: 26037552 Free PMC article.
Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity.
Lofgren S, Hinchcliff M, Carns M, Wood T, Aren K, Arroyo E, Cheung P, Kuo A, Valenzuela A, Haemel A, Wolters PJ, Gordon J, Spiera R, Assassi S, Boin F, Chung L, Fiorentino D, Utz PJ, Whitfield ML, Khatri P. Lofgren S, et al. Among authors: utz pj. JCI Insight. 2016 Dec 22;1(21):e89073. doi: 10.1172/jci.insight.89073. JCI Insight. 2016. PMID: 28018971 Free PMC article.
210 results