Utt A - Search Results

1

Design and Validation of Novel Chikungunya Virus Protease Inhibitors.

Das PK, Puusepp L, Varghese FS, Utt A, Ahola T, Kananovich DG, Lopp M, Merits A, Karelson M. Das PK, et al. Among authors: utt a. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7382-7395. doi: 10.1128/AAC.01421-16. Print 2016 Dec. Antimicrob Agents Chemother. 2016. PMID: 27736770 Free PMC article.

2

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays.

Pohjala L, Utt A, Varjak M, Lulla A, Merits A, Ahola T, Tammela P. Pohjala L, et al. Among authors: utt a. PLoS One. 2011;6(12):e28923. doi: 10.1371/journal.pone.0028923. Epub 2011 Dec 19. PLoS One. 2011. PMID: 22205980 Free PMC article.

3

Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2.

Utt A, Das PK, Varjak M, Lulla V, Lulla A, Merits A. Utt A, et al. J Virol. 2015 Mar;89(6):3145-62. doi: 10.1128/JVI.03213-14. Epub 2014 Dec 31. J Virol. 2015. PMID: 25552719 Free PMC article.

4

Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein.

Utt A, Quirin T, Saul S, Hellström K, Ahola T, Merits A. Utt A, et al. PLoS One. 2016 Mar 10;11(3):e0151616. doi: 10.1371/journal.pone.0151616. eCollection 2016. PLoS One. 2016. PMID: 26963103 Free PMC article.

5

Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue.

Rausalu K, Utt A, Quirin T, Varghese FS, Žusinaite E, Das PK, Ahola T, Merits A. Rausalu K, et al. Among authors: utt a. Sci Rep. 2016 Nov 15;6:37124. doi: 10.1038/srep37124. Sci Rep. 2016. PMID: 27845418 Free PMC article.

6

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

Thaa B, Biasiotto R, Eng K, Neuvonen M, Götte B, Rheinemann L, Mutso M, Utt A, Varghese F, Balistreri G, Merits A, Ahola T, McInerney GM. Thaa B, et al. Among authors: utt a. J Virol. 2015 Nov;89(22):11420-37. doi: 10.1128/JVI.01579-15. Epub 2015 Sep 2. J Virol. 2015. PMID: 26339054 Free PMC article.

7

Correction for Utt et al., Mutations Conferring a Noncytotoxic Phenotype on Chikungunya Virus Replicons Compromise Enzymatic Properties of Nonstructural Protein 2.

Utt A, Das PK, Varjak M, Lulla V, Lulla A, Merits A. Utt A, et al. J Virol. 2016 Aug 12;90(17):8030. doi: 10.1128/JVI.01167-16. Print 2016 Sep 1. J Virol. 2016. PMID: 27520947 Free PMC article. No abstract available.

8

Partially Uncleaved Alphavirus Replicase Forms Spherule Structures in the Presence and Absence of RNA Template.

Hellström K, Kallio K, Utt A, Quirin T, Jokitalo E, Merits A, Ahola T. Hellström K, et al. Among authors: utt a. J Virol. 2017 Aug 24;91(18):e00787-17. doi: 10.1128/JVI.00787-17. Print 2017 Sep 15. J Virol. 2017. PMID: 28701392 Free PMC article.

9

A Chikungunya Virus trans-Replicase System Reveals the Importance of Delayed Nonstructural Polyprotein Processing for Efficient Replication Complex Formation in Mosquito Cells.

Bartholomeeusen K, Utt A, Coppens S, Rausalu K, Vereecken K, Ariën KK, Merits A. Bartholomeeusen K, et al. Among authors: utt a. J Virol. 2018 Jun 29;92(14):e00152-18. doi: 10.1128/JVI.00152-18. Print 2018 Jul 15. J Virol. 2018. PMID: 29695432 Free PMC article.

10

Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase.

Law YS, Utt A, Tan YB, Zheng J, Wang S, Chen MW, Griffin PR, Merits A, Luo D. Law YS, et al. Among authors: utt a. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9558-9567. doi: 10.1073/pnas.1900656116. Epub 2019 Apr 18. Proc Natl Acad Sci U S A. 2019. PMID: 31000599 Free PMC article.

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