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TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure.
Lorenzana-Carrillo MA, Gopal K, Byrne NJ, Tejay S, Saleme B, Das SK, Zhang Y, Haromy A, Eaton F, Mendiola Pla M, Bowles DE, Dyck JRB, Ussher JR, Michelakis ED, Sutendra G. Lorenzana-Carrillo MA, et al. Among authors: ussher jr. Sci Transl Med. 2022 Nov 2;14(669):eabm3565. doi: 10.1126/scitranslmed.abm3565. Epub 2022 Nov 2. Sci Transl Med. 2022. PMID: 36322626
Lipotoxicity in obesity and diabetes-related cardiac dysfunction.
Zlobine I, Gopal K, Ussher JR. Zlobine I, et al. Among authors: ussher jr. Biochim Biophys Acta. 2016 Oct;1861(10):1555-68. doi: 10.1016/j.bbalip.2016.02.011. Epub 2016 Feb 18. Biochim Biophys Acta. 2016. PMID: 26899197 Review.
Sugar-sweetened beverages and vascular function: food for thought.
Gopal K, Ussher JR. Gopal K, et al. Among authors: ussher jr. Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H285-H288. doi: 10.1152/ajpheart.00783.2016. Epub 2016 Dec 30. Am J Physiol Heart Circ Physiol. 2017. PMID: 28039204 Free article. No abstract available.
FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression.
Gopal K, Saleme B, Al Batran R, Aburasayn H, Eshreif A, Ho KL, Ma WK, Almutairi M, Eaton F, Gandhi M, Park EA, Sutendra G, Ussher JR. Gopal K, et al. Among authors: ussher jr. Am J Physiol Heart Circ Physiol. 2017 Sep 1;313(3):H479-H490. doi: 10.1152/ajpheart.00191.2017. Epub 2017 Jul 7. Am J Physiol Heart Circ Physiol. 2017. PMID: 28687587 Free article.
107 results