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Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability.
J Med Chem. 2023 Dec 14;66(23):16426-16440. doi: 10.1021/acs.jmedchem.3c01876. Epub 2023 Nov 22.
J Med Chem. 2023.
PMID: 37992202
Structural basis of the activation of PPARγ by the plasticizer metabolites MEHP and MINCH.
Useini A, Engelberger F, Künze G, Sträter N.
Useini A, et al.
Environ Int. 2023 Mar;173:107822. doi: 10.1016/j.envint.2023.107822. Epub 2023 Feb 18.
Environ Int. 2023.
PMID: 36841188
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Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV-2 Main Protease Inhibitors as Antiviral Drugs.
Breidenbach J, Voget R, Si Y, Hingst A, Claff T, Sylvester K, Wolf V, Krasniqi V, Useini A, Sträter N, Ogura Y, Kawaguchi A, Müller CE, Gütschow M.
Breidenbach J, et al. Among authors: useini a.
J Med Chem. 2024 May 16. doi: 10.1021/acs.jmedchem.4c00053. Online ahead of print.
J Med Chem. 2024.
PMID: 38753594
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