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Erythroid SLC7A5/SLC3A2 amino acid carrier controls red blood cell size and maturation.
Bouthelier A, Fernández-Arroyo L, Mesa-Ciller C, Cibrian D, Martín-Cófreces NB, Castillo-González R, Calero M, Herráez-Aguilar D, Guajardo-Grence A, Pacheco AM, Marcos-Jiménez A, Quiroga B, Morado M, Monroy F, Muñoz-Calleja C, Sánchez-Madrid F, Urrutia AA, Aragonés J. Bouthelier A, et al. Among authors: urrutia aa. iScience. 2022 Dec 5;26(1):105739. doi: 10.1016/j.isci.2022.105739. eCollection 2023 Jan 20. iScience. 2022. PMID: 36582828 Free PMC article.
HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation.
Urrutia AA, Mesa-Ciller C, Guajardo-Grence A, Alkan HF, Soro-Arnáiz I, Vandekeere A, Ferreira Campos AM, Igelmann S, Fernández-Arroyo L, Rinaldi G, Lorendeau D, De Bock K, Fendt SM, Aragonés J. Urrutia AA, et al. Cell Rep. 2024 Apr 23;43(4):114103. doi: 10.1016/j.celrep.2024.114103. Epub 2024 Apr 11. Cell Rep. 2024. PMID: 38607920 Free PMC article.
Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro.
Pescador N, Francisco V, Vázquez P, Esquinas EM, González-Páramos C, Valdecantos MP, García-Martínez I, Urrutia AA, Ruiz L, Escalona-Garrido C, Foretz M, Viollet B, Fernández-Moreno MÁ, Calle-Pascual AL, Obregón MJ, Aragonés J, Valverde ÁM. Pescador N, et al. Among authors: urrutia aa. Redox Biol. 2021 Oct 19;48:102171. doi: 10.1016/j.redox.2021.102171. Online ahead of print. Redox Biol. 2021. PMID: 34736121 Free PMC article.
HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis.
Meléndez-Rodríguez F, Urrutia AA, Lorendeau D, Rinaldi G, Roche O, Böğürcü-Seidel N, Ortega Muelas M, Mesa-Ciller C, Turiel G, Bouthelier A, Hernansanz-Agustín P, Elorza A, Escasany E, Li QOY, Torres-Capelli M, Tello D, Fuertes E, Fraga E, Martínez-Ruiz A, Pérez B, Giménez-Bachs JM, Salinas-Sánchez AS, Acker T, Sánchez Prieto R, Fendt SM, De Bock K, Aragonés J. Meléndez-Rodríguez F, et al. Among authors: urrutia aa. Cell Rep. 2019 Feb 26;26(9):2257-2265.e4. doi: 10.1016/j.celrep.2019.01.106. Cell Rep. 2019. PMID: 30811976 Free article.
HIF Oxygen Sensing Pathways in Lung Biology.
Urrutia AA, Aragonés J. Urrutia AA, et al. Biomedicines. 2018 Jun 6;6(2):68. doi: 10.3390/biomedicines6020068. Biomedicines. 2018. PMID: 29882755 Free PMC article. Review.
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