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Pictolysin-III, a Hemorrhagic Type-III Metalloproteinase Isolated from Bothrops pictus (Serpentes: Viperidae) Venom, Reduces Mitochondrial Respiration and Induces Cytokine Secretion in Epithelial and Stromal Cell Lines.
Vivas-Ruiz DE, Rosas P, Proleón A, Torrejón D, Lazo F, Tenorio-Ricca AB, Guajardo F, Almarza C, Andrades V, Astorga J, Oropesa D, Toledo J, Vera MJ, Martínez J, Araya-Maturana R, Dubois-Camacho K, Hermoso MA, Alvarenga VG, Sanchez EF, Yarlequé A, Oliveira LS, Urra FA. Vivas-Ruiz DE, et al. Among authors: urra fa. Pharmaceutics. 2023 May 18;15(5):1533. doi: 10.3390/pharmaceutics15051533. Pharmaceutics. 2023. PMID: 37242775 Free PMC article.
Mitochondria: a promising target for anticancer alkaloids.
Urra FA, Cordova-Delgado M, Pessoa-Mahana H, Ramírez-Rodríguez O, Weiss-Lopez B, Ferreira J, Araya-Maturana R. Urra FA, et al. Curr Top Med Chem. 2013;13(17):2171-83. doi: 10.2174/15680266113139990150. Curr Top Med Chem. 2013. PMID: 23978135 Review.
Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation.
Urra FA, Córdova-Delgado M, Lapier M, Orellana-Manzano A, Acevedo-Arévalo L, Pessoa-Mahana H, González-Vivanco JM, Martínez-Cifuentes M, Ramírez-Rodríguez O, Millas-Vargas JP, Weiss-López B, Pavani M, Ferreira J, Araya-Maturana R. Urra FA, et al. Toxicol Appl Pharmacol. 2016 Jan 15;291:46-57. doi: 10.1016/j.taap.2015.12.005. Epub 2015 Dec 19. Toxicol Appl Pharmacol. 2016. PMID: 26712467
Fibrinogen-clotting enzyme, pictobin, from Bothrops pictus snake venom. Structural and functional characterization.
Vivas-Ruiz DE, Sandoval GA, Gonzalez-Kozlova E, Zarria-Romero J, Lazo F, Rodríguez E, Magalhães HPB, Chávez-Olortegui C, Oliveira LS, Alvarenga VG, Urra FA, Toledo J, Yarlequé A, Eble JA, Sanchez EF. Vivas-Ruiz DE, et al. Among authors: urra fa. Int J Biol Macromol. 2020 Jun 15;153:779-795. doi: 10.1016/j.ijbiomac.2020.03.055. Epub 2020 Mar 10. Int J Biol Macromol. 2020. PMID: 32169454
38 results