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Metabolic rewiring induced by ranolazine improves melanoma responses to targeted therapy and immunotherapy.
Redondo-Muñoz M, Rodriguez-Baena FJ, Aldaz P, Caballé-Mestres A, Moncho-Amor V, Otaegi-Ugartemendia M, Carrasco-Garcia E, Olias-Arjona A, Lasheras-Otero I, Santamaria E, Bocanegra A, Chocarro L, Grier A, Dzieciatkowska M M, Bigas C, Martin J, Urdiroz-Urricelqui U, Marzo F, Santamaria E, Kochan G, Escors D, Larrayoz IM, Heyn H, D'Alessandro A, Attolini CS, Matheu A, Wellbrock C, Benitah SA, Sanchez-Laorden B, Arozarena I. Redondo-Muñoz M, et al. Among authors: urdiroz urricelqui u. Nat Metab. 2023 Sep;5(9):1544-1562. doi: 10.1038/s42255-023-00861-4. Epub 2023 Aug 10. Nat Metab. 2023. PMID: 37563469 Free PMC article.
The role of lipids in cancer progression and metastasis.
Martin-Perez M, Urdiroz-Urricelqui U, Bigas C, Benitah SA. Martin-Perez M, et al. Among authors: urdiroz urricelqui u. Cell Metab. 2022 Nov 1;34(11):1675-1699. doi: 10.1016/j.cmet.2022.09.023. Epub 2022 Oct 18. Cell Metab. 2022. PMID: 36261043 Free article. Review.
Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours.
Avgustinova A, Symeonidi A, Castellanos A, Urdiroz-Urricelqui U, Solé-Boldo L, Martín M, Pérez-Rodríguez I, Prats N, Lehner B, Supek F, Benitah SA. Avgustinova A, et al. Among authors: urdiroz urricelqui u. Nat Cell Biol. 2018 Dec;20(12):1400-1409. doi: 10.1038/s41556-018-0233-x. Epub 2018 Nov 19. Nat Cell Biol. 2018. PMID: 30455462 Free article.
Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development.
Avgustinova A, Laudanna C, Pascual-García M, Rovira Q, Djurec M, Castellanos A, Urdiroz-Urricelqui U, Marchese D, Prats N, Van Keymeulen A, Heyn H, Vaquerizas JM, Benitah SA. Avgustinova A, et al. Among authors: urdiroz urricelqui u. Cell Stem Cell. 2021 Oct 7;28(10):1790-1804.e8. doi: 10.1016/j.stem.2021.04.030. Epub 2021 May 18. Cell Stem Cell. 2021. PMID: 34010627 Free article.