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The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution.
Ballhausen A, Przybilla MJ, Jendrusch M, Haupt S, Pfaffendorf E, Seidler F, Witt J, Hernandez Sanchez A, Urban K, Draxlbauer M, Krausert S, Ahadova A, Kalteis MS, Pfuderer PL, Heid D, Stichel D, Gebert J, Bonsack M, Schott S, Bläker H, Seppälä T, Mecklin JP, Ten Broeke S, Nielsen M, Heuveline V, Krzykalla J, Benner A, Riemer AB, von Knebel Doeberitz M, Kloor M. Ballhausen A, et al. Among authors: urban k. Nat Commun. 2020 Sep 21;11(1):4740. doi: 10.1038/s41467-020-18514-5. Nat Commun. 2020. PMID: 32958755 Free PMC article.
Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model.
Gebert J, Gelincik O, Oezcan-Wahlbrink M, Marshall JD, Hernandez-Sanchez A, Urban K, Long M, Cortes E, Tosti E, Katzenmaier EM, Song Y, Elsaadi A, Deng N, Vilar E, Fuchs V, Nelius N, Yuan YP, Ahadova A, Sei S, Shoemaker RH, Umar A, Wei L, Liu S, Bork P, Edelmann W, von Knebel Doeberitz M, Lipkin SM, Kloor M. Gebert J, et al. Among authors: urban k. Gastroenterology. 2021 Oct;161(4):1288-1302.e13. doi: 10.1053/j.gastro.2021.06.073. Epub 2021 Jul 2. Gastroenterology. 2021. PMID: 34224739 Free PMC article.
No evidence of oncogenic KRAS mutations in squamous cell carcinomas of the anogenital tract and head and neck region independent of human papillomavirus and p16(INK4a) status.
Prigge ES, Urban K, Stiegler S, Müller M, Kloor M, Mai S, Ottstadt M, Lohr F, Wenz F, Wagner S, Wittekindt C, Klussmann JP, Hampl M, von Knebel Doeberitz M, Reuschenbach M. Prigge ES, et al. Among authors: urban k. Hum Pathol. 2014 Nov;45(11):2347-54. doi: 10.1016/j.humpath.2014.08.001. Epub 2014 Aug 23. Hum Pathol. 2014. PMID: 25257576
Macrophage-derived nitric oxide initiates T-cell diapedesis and tumor rejection.
Sektioglu IM, Carretero R, Bender N, Bogdan C, Garbi N, Umansky V, Umansky L, Urban K, von Knebel-Döberitz M, Somasundaram V, Wink D, Beckhove P, Hämmerling GJ. Sektioglu IM, et al. Among authors: urban k. Oncoimmunology. 2016 Aug 9;5(10):e1204506. doi: 10.1080/2162402X.2016.1204506. eCollection 2016. Oncoimmunology. 2016. PMID: 27853636 Free PMC article.
The fentanyl-specific antibody FenAb024 can shield against carfentanil effects.
Urban K, Gkeka A, Chandra M, Greiner D, Pollich S, Ruf S, Kelemen Y, Sundermann T, Pravetoni M, Baehr C, Stebbins CE, Papavasiliou FN, Verdi JP. Urban K, et al. Toxicol Lett. 2024 May 15;396:1-10. doi: 10.1016/j.toxlet.2024.03.008. Epub 2024 Apr 6. Toxicol Lett. 2024. PMID: 38588756 Free article.
261 results