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A first-in-class, first-in-human, phase I trial of CIGB-552, a synthetic peptide targeting COMMD1 to inhibit the oncogenic activity of NF-κB in patients with advanced solid tumors.
Vallespi MG, Mestre B, Marrero MA, Uranga R, Rey D, Lugiollo M, Betancourt M, Silva K, Corrales D, Lamadrid Y, Rodriguez Y, Maceo A, Chaviano PP, Lemos G, Cabrales A, Freyre FM, Santana H, Garay HE, Oliva B, Fernandez JR. Vallespi MG, et al. Among authors: uranga r. Int J Cancer. 2021 Sep 15;149(6):1313-1321. doi: 10.1002/ijc.33695. Epub 2021 May 27. Int J Cancer. 2021. PMID: 34019700 Free article. Clinical Trial.
Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
Mori H, Peterson SK, Simmermon RC, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung JN, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA. Mori H, et al. Among authors: uranga rm. Mol Metab. 2024 May;83:101916. doi: 10.1016/j.molmet.2024.101916. Epub 2024 Mar 14. Mol Metab. 2024. PMID: 38492843 Free PMC article.
Genetic susceptibility for retinopathy of prematurity and its associated comorbidities.
Gimenez LG, Gili JA, Elias DE, Sagula R, Comas B, Santos MR, Campaña H, Poletta FA, Heisecke SL, Ratowiecki J, Cosentino VR, Uranga R, Saleme C, Negri M, Rittler M, Zapata Barrios J, Krupitzki HB, López Camelo JS. Gimenez LG, et al. Among authors: uranga r. Pediatr Res. 2024 Feb 12. doi: 10.1038/s41390-024-03068-9. Online ahead of print. Pediatr Res. 2024. PMID: 38347174
Gene-environment interactions and preterm birth predictors: A Bayesian network approach.
Elias DE, Santos MR, Campaña H, Poletta FA, Heisecke SL, Gili JA, Ratowiecki J, Cosentino VR, Uranga R, Málaga DR, Oliveira Netto AB, Brusius-Facchin AC, Saleme C, Rittler M, Krupitzki HB, Camelo JSL, Gimenez LG. Elias DE, et al. Among authors: uranga r. Genet Mol Biol. 2024 Jan 19;46(4):e20230090. doi: 10.1590/1678-4685-GMB-2023-0090. eCollection 2024. Genet Mol Biol. 2024. PMID: 38285431 Free PMC article.
SCD1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
Mori H, Peterson SK, Simmermon R, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung J, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA. Mori H, et al. Among authors: uranga rm. bioRxiv [Preprint]. 2023 Oct 27:2023.10.27.564376. doi: 10.1101/2023.10.27.564376. bioRxiv. 2023. PMID: 37961537 Free PMC article. Updated. Preprint.
Diseases during pregnancy in a large unselected South American sample.
Santos MR, Campaña H, Heisecke S, Ratowiecki J, Elías D, Giménez L, Poletta FA, Gili J, Uranga R, Cosentino V, Krupitzki H, Rittler M, Camelo JL. Santos MR, et al. Among authors: uranga r. Rev Bras Epidemiol. 2022 Dec 5;25:e220043. doi: 10.1590/1980-549720220043. eCollection 2022. Rev Bras Epidemiol. 2022. PMID: 36478216 Free article.
Genes, exposures, and interactions on preterm birth risk: an exploratory study in an Argentine population.
Elias DE, Santos MR, Campaña H, Poletta FA, Heisecke SL, Gili JA, Ratowiecki J, Cosentino V, Uranga R, Málaga DR, Netto ABO, Brusius-Facchin AC, Saleme C, Rittler M, Krupitzki HB, Camelo JSL, Gimenez LG. Elias DE, et al. Among authors: uranga r. J Community Genet. 2022 Dec;13(6):557-565. doi: 10.1007/s12687-022-00605-z. Epub 2022 Aug 17. J Community Genet. 2022. PMID: 35976607 Free PMC article.
41 results