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An efficient synthesis of new caffeine-based chalcones, pyrazolines and pyrazolo[3,4-b][1,4]diazepines as potential antimalarial, antitrypanosomal and antileishmanial agents.
Insuasty B, Ramírez J, Becerra D, Echeverry C, Quiroga J, Abonia R, Robledo SM, Vélez ID, Upegui Y, Muñoz JA, Ospina V, Nogueras M, Cobo J. Insuasty B, et al. Among authors: upegui y. Eur J Med Chem. 2015 Mar 26;93:401-13. doi: 10.1016/j.ejmech.2015.02.040. Epub 2015 Feb 21. Eur J Med Chem. 2015. PMID: 25725376
Antileishmanial activity and cytotoxicity of ent-beyerene diterpenoids.
Murillo JA, Gil JF, Upegui YA, Restrepo AM, Robledo SM, Quiñones W, Echeverri F, San Martin A, Olivo HF, Escobar G. Murillo JA, et al. Among authors: upegui ya. Bioorg Med Chem. 2019 Jan 1;27(1):153-160. doi: 10.1016/j.bmc.2018.11.030. Epub 2018 Nov 22. Bioorg Med Chem. 2019. PMID: 30482546
17 results