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A Critical Role for Fas-Mediated Off-Target Tumor Killing in T-cell Immunotherapy.
Upadhyay R, Boiarsky JA, Pantsulaia G, Svensson-Arvelund J, Lin MJ, Wroblewska A, Bhalla S, Scholler N, Bot A, Rossi JM, Sadek N, Parekh S, Lagana A, Baccarini A, Merad M, Brown BD, Brody JD. Upadhyay R, et al. Cancer Discov. 2021 Mar;11(3):599-613. doi: 10.1158/2159-8290.CD-20-0756. Epub 2020 Dec 17. Cancer Discov. 2021. PMID: 33334730 Free PMC article.
Lymphoma: immune evasion strategies.
Upadhyay R, Hammerich L, Peng P, Brown B, Merad M, Brody JD. Upadhyay R, et al. Cancers (Basel). 2015 Apr 30;7(2):736-62. doi: 10.3390/cancers7020736. Cancers (Basel). 2015. PMID: 25941795 Free PMC article. Review.
Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination.
Hammerich L, Marron TU, Upadhyay R, Svensson-Arvelund J, Dhainaut M, Hussein S, Zhan Y, Ostrowski D, Yellin M, Marsh H, Salazar AM, Rahman AH, Brown BD, Merad M, Brody JD. Hammerich L, et al. Among authors: upadhyay r. Nat Med. 2019 May;25(5):814-824. doi: 10.1038/s41591-019-0410-x. Epub 2019 Apr 8. Nat Med. 2019. PMID: 30962585 Clinical Trial.
Expanding cross-presenting dendritic cells enhances oncolytic virotherapy and is critical for long-term anti-tumor immunity.
Svensson-Arvelund J, Cuadrado-Castano S, Pantsulaia G, Kim K, Aleynick M, Hammerich L, Upadhyay R, Yellin M, Marsh H, Oreper D, Jhunjhunwala S, Moussion C, Merad M, Brown BD, García-Sastre A, Brody JD. Svensson-Arvelund J, et al. Among authors: upadhyay r. Nat Commun. 2022 Nov 22;13(1):7149. doi: 10.1038/s41467-022-34791-8. Nat Commun. 2022. PMID: 36418317 Free PMC article.
Comparative analysis of the tumor microbiome, molecular profiles, and immune cell abundances by HPV status in mucosal head and neck cancers and their impact on survival.
Upadhyay R, Dhakal A, Wheeler C, Hoyd R, Jagjit Singh M, Karivedu V, Bhateja P, Bonomi M, Valentin S, Gamez ME, Konieczkowski DJ, Baliga S, Grecula JC, Blakaj DM, Gogineni E, Mitchell DL, Denko NC, Spakowicz D, Jhawar SR. Upadhyay R, et al. Cancer Biol Ther. 2024 Dec 31;25(1):2350249. doi: 10.1080/15384047.2024.2350249. Epub 2024 May 9. Cancer Biol Ther. 2024. PMID: 38722731
515 results