Ung PM - Search Results

1

Type II Binders Targeting the "GLR-Out" Conformation of the Pseudokinase STRADα.

Smith RHB, Khan ZM, Ung PM, Scopton AP, Silber L, Mack SM, Real AM, Schlessinger A, Dar AC. Smith RHB, et al. Among authors: ung pm. Biochemistry. 2021 Feb 2;60(4):289-302. doi: 10.1021/acs.biochem.0c00714. Epub 2021 Jan 13. Biochemistry. 2021. PMID: 33440120 Free PMC article.

2

DFGmodel: predicting protein kinase structures in inactive states for structure-based discovery of type-II inhibitors.

Ung PM, Schlessinger A. Ung PM, et al. ACS Chem Biol. 2015 Jan 16;10(1):269-78. doi: 10.1021/cb500696t. Epub 2014 Dec 9. ACS Chem Biol. 2015. PMID: 25420233 Free PMC article.

3

Redefining the Protein Kinase Conformational Space with Machine Learning.

Ung PM, Rahman R, Schlessinger A. Ung PM, et al. Cell Chem Biol. 2018 Jul 19;25(7):916-924.e2. doi: 10.1016/j.chembiol.2018.05.002. Epub 2018 May 31. Cell Chem Biol. 2018. PMID: 29861272 Free PMC article.

4

KinaMetrix: a web resource to investigate kinase conformations and inhibitor space.

Rahman R, Ung PM, Schlessinger A. Rahman R, et al. Among authors: ung pm. Nucleic Acids Res. 2019 Jan 8;47(D1):D361-D366. doi: 10.1093/nar/gky916. Nucleic Acids Res. 2019. PMID: 30321373 Free PMC article.

5

SLC Transporters: Structure, Function, and Drug Discovery.

Colas C, Ung PM, Schlessinger A. Colas C, et al. Among authors: ung pm. Medchemcomm. 2016 Jun 1;7(6):1069-1081. doi: 10.1039/C6MD00005C. Epub 2016 Mar 28. Medchemcomm. 2016. PMID: 27672436 Free PMC article.

6

Encounter and React: Computer-Guided Design of Covalent Inhibitors.

Ung PM, DeVita RJ, Schlessinger A. Ung PM, et al. Cell Chem Biol. 2019 Jan 17;26(1):6-8. doi: 10.1016/j.chembiol.2018.12.009. Cell Chem Biol. 2019. PMID: 30658111 Free article.

7

Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening.

Ung PM, Song W, Cheng L, Zhao X, Hu H, Chen L, Schlessinger A. Ung PM, et al. ACS Chem Biol. 2016 Jul 15;11(7):1908-16. doi: 10.1021/acschembio.6b00304. Epub 2016 May 11. ACS Chem Biol. 2016. PMID: 27128978 Free PMC article.

8

Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase.

Truong TH, Ung PM, Palde PB, Paulsen CE, Schlessinger A, Carroll KS. Truong TH, et al. Among authors: ung pm. Cell Chem Biol. 2016 Jul 21;23(7):837-848. doi: 10.1016/j.chembiol.2016.05.017. Epub 2016 Jul 14. Cell Chem Biol. 2016. PMID: 27427230 Free PMC article.

9

Structures of ligand-occupied β-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity.

Kuzina ES, Ung PM, Mohanty J, Tome F, Choi J, Pardon E, Steyaert J, Lax I, Schlessinger A, Schlessinger J, Lee S. Kuzina ES, et al. Among authors: ung pm. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7819-7824. doi: 10.1073/pnas.1822055116. Epub 2019 Apr 3. Proc Natl Acad Sci U S A. 2019. PMID: 30944224 Free PMC article.

10

Identification of a G-Protein-Independent Activator of GIRK Channels.

Zhao Y, Ung PM, Zahoránszky-Kőhalmi G, Zakharov AV, Martinez NJ, Simeonov A, Glaaser IW, Rai G, Schlessinger A, Marugan JJ, Slesinger PA. Zhao Y, et al. Among authors: ung pm. Cell Rep. 2020 Jun 16;31(11):107770. doi: 10.1016/j.celrep.2020.107770. Cell Rep. 2020. PMID: 32553165 Free PMC article.

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