Unciti-Broceta A - Search Results

1

Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics.

Ortega-Liebana MC, Porter NJ, Adam C, Valero T, Hamilton L, Sieger D, Becker CG, Unciti-Broceta A. Ortega-Liebana MC, et al. Angew Chem Weinheim Bergstr Ger. 2022 Jan 3;134(1):e202111461. doi: 10.1002/ange.202111461. Epub 2021 Nov 18. Angew Chem Weinheim Bergstr Ger. 2022. PMID: 38505566 Free PMC article.

2

Gold-Triggered Uncaging Chemistry in Living Systems.

Pérez-López AM, Rubio-Ruiz B, Sebastián V, Hamilton L, Adam C, Bray TL, Irusta S, Brennan PM, Lloyd-Jones GC, Sieger D, Santamaría J, Unciti-Broceta A. Pérez-López AM, et al. Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12548-12552. doi: 10.1002/anie.201705609. Epub 2017 Aug 9. Angew Chem Int Ed Engl. 2017. PMID: 28699691 Free PMC article.

3

Metallofluorescent Nanoparticles for Multimodal Applications.

Delgado-Gonzalez A, Garcia-Fernandez E, Valero T, Cano-Cortes MV, Ruedas-Rama MJ, Unciti-Broceta A, Sanchez-Martin RM, Diaz-Mochon JJ, Orte A. Delgado-Gonzalez A, et al. ACS Omega. 2018 Jan 31;3(1):144-153. doi: 10.1021/acsomega.7b01984. Epub 2018 Jan 5. ACS Omega. 2018. PMID: 30023770 Free PMC article.

4

Drug "Clicking" on Cell-Penetrating Fluorescent Nanoparticles for In Cellulo Chemical Proteomics.

Valero T, Delgado-González A, Unciti-Broceta JD, Cano-Cortés V, Pérez-López AM, Unciti-Broceta A, Sánchez Martín RM. Valero T, et al. Bioconjug Chem. 2018 Sep 19;29(9):3154-3160. doi: 10.1021/acs.bioconjchem.8b00481. Epub 2018 Sep 4. Bioconjug Chem. 2018. PMID: 30122043 Free article.

5

Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices.

Adam C, Pérez-López AM, Hamilton L, Rubio-Ruiz B, Bray TL, Sieger D, Brennan PM, Unciti-Broceta A. Adam C, et al. Chemistry. 2018 Nov 13;24(63):16783-16790. doi: 10.1002/chem.201803725. Epub 2018 Nov 8. Chemistry. 2018. PMID: 30187973 Free PMC article.

6

Pyrazolopyrimide library screening in glioma cells discovers highly potent antiproliferative leads that target the PI3K/mTOR pathway.

Valero T, Baillache DJ, Fraser C, Myers SH, Unciti-Broceta A. Valero T, et al. Bioorg Med Chem. 2020 Jan 1;28(1):115215. doi: 10.1016/j.bmc.2019.115215. Epub 2019 Nov 25. Bioorg Med Chem. 2020. PMID: 31787462 Free PMC article.

7

Bioorthogonal Uncaging of Cytotoxic Paclitaxel through Pd Nanosheet-Hydrogel Frameworks.

Pérez-López AM, Rubio-Ruiz B, Valero T, Contreras-Montoya R, Álvarez de Cienfuegos L, Sebastián V, Santamaría J, Unciti-Broceta A. Pérez-López AM, et al. J Med Chem. 2020 Sep 10;63(17):9650-9659. doi: 10.1021/acs.jmedchem.0c00781. Epub 2020 Aug 17. J Med Chem. 2020. PMID: 32787091 Free PMC article.

8

Transition metal catalysts for the bioorthogonal synthesis of bioactive agents.

van de L'Isle MON, Ortega-Liebana MC, Unciti-Broceta A. van de L'Isle MON, et al. Curr Opin Chem Biol. 2021 Apr;61:32-42. doi: 10.1016/j.cbpa.2020.10.001. Epub 2020 Nov 2. Curr Opin Chem Biol. 2021. PMID: 33147552 Free article. Review.

9

A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability.

Temps C, Lietha D, Webb ER, Li XF, Dawson JC, Muir M, Macleod KG, Valero T, Munro AF, Contreras-Montoya R, Luque-Ortega JR, Fraser C, Beetham H, Schoenherr C, Lopalco M, Arends MJ, Frame MC, Qian BZ, Brunton VG, Carragher NO, Unciti-Broceta A. Temps C, et al. Cancer Res. 2021 Nov 1;81(21):5438-5450. doi: 10.1158/0008-5472.CAN-21-0613. Epub 2021 Aug 20. Cancer Res. 2021. PMID: 34417202 Free PMC article.

10

Small Molecule Kinase Inhibitor Drugs (1995-2021): Medical Indication, Pharmacology, and Synthesis.

Ayala-Aguilera CC, Valero T, Lorente-Macías Á, Baillache DJ, Croke S, Unciti-Broceta A. Ayala-Aguilera CC, et al. J Med Chem. 2022 Jan 27;65(2):1047-1131. doi: 10.1021/acs.jmedchem.1c00963. Epub 2021 Oct 8. J Med Chem. 2022. PMID: 34624192 Free article. Review.

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