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The Neglected Liaison: Targeting Cancer Cell Metabolic Reprogramming Modifies the Composition of Non-Malignant Populations of the Tumor Microenvironment.
Cancers (Basel). 2021 Oct 29;13(21):5447. doi: 10.3390/cancers13215447.
Cancers (Basel). 2021.
PMID: 34771610
Free PMC article.
Review.
The multifaceted effects of metformin on tumor microenvironment.
Kurelac I, Umesh Ganesh N, Iorio M, Porcelli AM, Gasparre G.
Kurelac I, et al. Among authors: umesh ganesh n.
Semin Cell Dev Biol. 2020 Feb;98:90-97. doi: 10.1016/j.semcdb.2019.05.010. Epub 2019 May 22.
Semin Cell Dev Biol. 2020.
PMID: 31091466
Free article.
Review.
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A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma.
Kurelac I, Abarrategi A, Ragazzi M, Iommarini L, Umesh Ganesh N, Snoeks T, Bonnet D, Porcelli AM, Malanchi I, Gasparre G.
Kurelac I, et al. Among authors: umesh ganesh n.
J Clin Med. 2019 Dec 11;8(12):2184. doi: 10.3390/jcm8122184.
J Clin Med. 2019.
PMID: 31835761
Free PMC article.
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NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate.
D'Angelo L, Astro E, De Luise M, Kurelac I, Umesh-Ganesh N, Ding S, Fearnley IM, Gasparre G, Zeviani M, Porcelli AM, Fernandez-Vizarra E, Iommarini L.
D'Angelo L, et al. Among authors: umesh ganesh n.
Cell Rep. 2021 Apr 20;35(3):109002. doi: 10.1016/j.celrep.2021.109002.
Cell Rep. 2021.
PMID: 33882309
Free PMC article.
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Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.
Kurelac I, Iommarini L, Vatrinet R, Amato LB, De Luise M, Leone G, Girolimetti G, Umesh Ganesh N, Bridgeman VL, Ombrato L, Columbaro M, Ragazzi M, Gibellini L, Sollazzo M, Feichtinger RG, Vidali S, Baldassarre M, Foriel S, Vidone M, Cossarizza A, Grifoni D, Kofler B, Malanchi I, Porcelli AM, Gasparre G.
Kurelac I, et al. Among authors: umesh ganesh n.
Nat Commun. 2019 Feb 22;10(1):903. doi: 10.1038/s41467-019-08839-1.
Nat Commun. 2019.
PMID: 30796225
Free PMC article.
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Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications.
Liu W, Stachura P, Xu HC, Umesh Ganesh N, Cox F, Wang R, Lang KS, Gopalakrishnan J, Häussinger D, Homey B, Lang PA, Pandyra AA.
Liu W, et al. Among authors: umesh ganesh n.
J Exp Clin Cancer Res. 2020 Feb 21;39(1):38. doi: 10.1186/s13046-020-1539-7.
J Exp Clin Cancer Res. 2020.
PMID: 32085796
Free PMC article.
Item in Clipboard
Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target.
Gampala S, Shah F, Lu X, Moon HR, Babb O, Umesh Ganesh N, Sandusky G, Hulsey E, Armstrong L, Mosely AL, Han B, Ivan M, Yeh JJ, Kelley MR, Zhang C, Fishel ML.
Gampala S, et al. Among authors: umesh ganesh n.
J Exp Clin Cancer Res. 2021 Aug 10;40(1):251. doi: 10.1186/s13046-021-02046-x.
J Exp Clin Cancer Res. 2021.
PMID: 34376225
Free PMC article.
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