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The multifaceted effects of metformin on tumor microenvironment.
Kurelac I, Umesh Ganesh N, Iorio M, Porcelli AM, Gasparre G. Kurelac I, et al. Among authors: umesh ganesh n. Semin Cell Dev Biol. 2020 Feb;98:90-97. doi: 10.1016/j.semcdb.2019.05.010. Epub 2019 May 22. Semin Cell Dev Biol. 2020. PMID: 31091466 Free article. Review.
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.
Kurelac I, Iommarini L, Vatrinet R, Amato LB, De Luise M, Leone G, Girolimetti G, Umesh Ganesh N, Bridgeman VL, Ombrato L, Columbaro M, Ragazzi M, Gibellini L, Sollazzo M, Feichtinger RG, Vidali S, Baldassarre M, Foriel S, Vidone M, Cossarizza A, Grifoni D, Kofler B, Malanchi I, Porcelli AM, Gasparre G. Kurelac I, et al. Among authors: umesh ganesh n. Nat Commun. 2019 Feb 22;10(1):903. doi: 10.1038/s41467-019-08839-1. Nat Commun. 2019. PMID: 30796225 Free PMC article.
Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target.
Gampala S, Shah F, Lu X, Moon HR, Babb O, Umesh Ganesh N, Sandusky G, Hulsey E, Armstrong L, Mosely AL, Han B, Ivan M, Yeh JJ, Kelley MR, Zhang C, Fishel ML. Gampala S, et al. Among authors: umesh ganesh n. J Exp Clin Cancer Res. 2021 Aug 10;40(1):251. doi: 10.1186/s13046-021-02046-x. J Exp Clin Cancer Res. 2021. PMID: 34376225 Free PMC article.