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Induction of human cardiomyocyte-like cells from fibroblasts by defined factors.
Wada R, Muraoka N, Inagawa K, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Kaneda R, Suzuki T, Kamiya K, Tohyama S, Yuasa S, Kokaji K, Aeba R, Yozu R, Yamagishi H, Kitamura T, Fukuda K, Ieda M. Wada R, et al. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12667-72. doi: 10.1073/pnas.1304053110. Epub 2013 Jul 16. Proc Natl Acad Sci U S A. 2013. PMID: 23861494 Free PMC article. Clinical Trial.
MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.
Muraoka N, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Isomi M, Nakashima H, Akiyama M, Wada R, Inagawa K, Nishiyama T, Kaneda R, Fukuda T, Takeda S, Tohyama S, Hashimoto H, Kawamura Y, Goshima N, Aeba R, Yamagishi H, Fukuda K, Ieda M. Muraoka N, et al. EMBO J. 2014 Jul 17;33(14):1565-81. doi: 10.15252/embj.201387605. Epub 2014 Jun 11. EMBO J. 2014. PMID: 24920580 Free PMC article.
Single-Construct Polycistronic Doxycycline-Inducible Vectors Improve Direct Cardiac Reprogramming and Can Be Used to Identify the Critical Timing of Transgene Expression.
Umei TC, Yamakawa H, Muraoka N, Sadahiro T, Isomi M, Haginiwa S, Kojima H, Kurotsu S, Tamura F, Osakabe R, Tani H, Nara K, Miyoshi H, Fukuda K, Ieda M. Umei TC, et al. Int J Mol Sci. 2017 Aug 19;18(8):1805. doi: 10.3390/ijms18081805. Int J Mol Sci. 2017. PMID: 28825623 Free PMC article.
Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells.
Someya S, Tohyama S, Kameda K, Tanosaki S, Morita Y, Sasaki K, Kang MI, Kishino Y, Okada M, Tani H, Soma Y, Nakajima K, Umei T, Sekine O, Moriwaki T, Kanazawa H, Kobayashi E, Fujita J, Fukuda K. Someya S, et al. iScience. 2021 Jan 26;24(2):102090. doi: 10.1016/j.isci.2021.102090. eCollection 2021 Feb 19. iScience. 2021. PMID: 33615198 Free PMC article.
Transcatheter Mitral Valve Repair Effective and Safe for Refractory Eclipsed Mitral Regurgitation-Induced Cardiogenic Shock: A Case Report.
Umei TC, Shiraishi Y, Tsuruta H, Hayashida K, Imaeda S, Ryuzaki T, Myojin S, Kobari Y, Saito T, Yoshijima N, Itabashi Y, Kishino Y, Katsumata Y, Yuasa S, Fukuda K. Umei TC, et al. Circ Cardiovasc Imaging. 2021 Jul;14(7):e012641. doi: 10.1161/CIRCIMAGING.121.012641. Epub 2021 Jul 8. Circ Cardiovasc Imaging. 2021. PMID: 34235938 No abstract available.
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