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Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types.
Umar S, Palasiewicz K, Volin MV, Romay B, Rahat R, Tetali C, Arami S, Guma M, Ascoli C, Sweiss N, Zomorrodi RK, O'Neill LAJ, Shahrara S. Umar S, et al. Cell Mol Life Sci. 2021 Dec;78(23):7693-7707. doi: 10.1007/s00018-021-03978-5. Epub 2021 Oct 27. Cell Mol Life Sci. 2021. PMID: 34705053 Free PMC article.
Metabolic reprogramming of macrophages instigates CCL21-induced arthritis.
Van Raemdonck K, Umar S, Palasiewicz K, Meyer A, Volin MV, Chang HJ, Al-Awqati M, Zomorrodi RK, Shahrara S. Van Raemdonck K, et al. Among authors: umar s. Immunol Cell Biol. 2022 Feb;100(2):127-135. doi: 10.1111/imcb.12512. Epub 2021 Dec 6. Immunol Cell Biol. 2022. PMID: 34779007 Free PMC article.
Macrophages are the primary effector cells in IL-7-induced arthritis.
Kim SJ, Chang HJ, Volin MV, Umar S, Van Raemdonck K, Chevalier A, Palasiewicz K, Christman JW, Volkov S, Arami S, Maz M, Mehta A, Zomorrodi RK, Fox DA, Sweiss N, Shahrara S. Kim SJ, et al. Among authors: umar s. Cell Mol Immunol. 2020 Jul;17(7):728-740. doi: 10.1038/s41423-019-0235-z. Epub 2019 Jun 13. Cell Mol Immunol. 2020. PMID: 31197255 Free PMC article.
455 results