Umaña P - Search Results

1

Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors.

Natoli M, Hatje K, Gulati P, Junker F, Herzig P, Jiang Z, Davydov II, Germann M, Trüb M, Marbach D, Zwick A, Weber P, Seeber S, Wiese M, Lardinois D, Heinzelmann-Schwarz V, Rosenberg R, Tietze L, Mertz KD, Umaña P, Klein C, Codarri-Deak L, Kao H, Zippelius A. Natoli M, et al. Among authors: umana p. J Immunother Cancer. 2022 Nov;10(11):e005548. doi: 10.1136/jitc-2022-005548. J Immunother Cancer. 2022. PMID: 36319064 Free PMC article.

2

Improved effector functions of a therapeutic monoclonal Lewis Y-specific antibody by glycoform engineering.

Schuster M, Umana P, Ferrara C, Brünker P, Gerdes C, Waxenecker G, Wiederkum S, Schwager C, Loibner H, Himmler G, Mudde GC. Schuster M, et al. Among authors: umana p. Cancer Res. 2005 Sep 1;65(17):7934-41. doi: 10.1158/0008-5472.CAN-04-4212. Cancer Res. 2005. PMID: 16140965

3

Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination.

Umaña P, Gerdes CA, Stone D, Davis JR, Ward D, Castro MG, Lowenstein PR. Umaña P, et al. Nat Biotechnol. 2001 Jun;19(6):582-5. doi: 10.1038/89349. Nat Biotechnol. 2001. PMID: 11385466

4

Phase I pharmacokinetic and pharmacodynamic dose-escalation study of RG7160 (GA201), the first glycoengineered monoclonal antibody against the epidermal growth factor receptor, in patients with advanced solid tumors.

Paz-Ares LG, Gomez-Roca C, Delord JP, Cervantes A, Markman B, Corral J, Soria JC, Bergé Y, Roda D, Russell-Yarde F, Hollingsworth S, Baselga J, Umana P, Manenti L, Tabernero J. Paz-Ares LG, et al. Among authors: umana p. J Clin Oncol. 2011 Oct 1;29(28):3783-90. doi: 10.1200/JCO.2011.34.8888. Epub 2011 Sep 6. J Clin Oncol. 2011. PMID: 21900113 Clinical Trial.

5

A novel combination of promoter and enhancers increases transgene expression in vascular smooth muscle cells in vitro and coronary arteries in vivo after adenovirus-mediated gene transfer.

Appleby CE, Kingston PA, David A, Gerdes CA, Umaña P, Castro MG, Lowenstein PR, Heagerty AM. Appleby CE, et al. Among authors: umana p. Gene Ther. 2003 Sep;10(18):1616-22. doi: 10.1038/sj.gt.3302044. Gene Ther. 2003. PMID: 12907954 Free PMC article.

6

High-capacity, helper-dependent, "gutless" adenoviral vectors for gene transfer into brain.

Lowenstein PR, Thomas CE, Umana P, Gerdes CA, Verakis T, Boyer O, Tondeur S, Klatzmann D, Castro MG. Lowenstein PR, et al. Among authors: umana p. Methods Enzymol. 2002;346:292-311. doi: 10.1016/s0076-6879(02)46062-4. Methods Enzymol. 2002. PMID: 11883074 No abstract available.

7

A small-scale method for the preparation of plant N-linked glycans from soluble proteins for analysis by MALDI-TOF mass spectrometry.

Karg SR, Frey AD, Ferrara C, Streich DK, Umaña P, Kallio PT. Karg SR, et al. Among authors: umana p. Plant Physiol Biochem. 2009 Feb;47(2):160-6. doi: 10.1016/j.plaphy.2008.10.005. Epub 2008 Oct 26. Plant Physiol Biochem. 2009. PMID: 19028106

8

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity.

Umaña P, Jean-Mairet J, Moudry R, Amstutz H, Bailey JE. Umaña P, et al. Nat Biotechnol. 1999 Feb;17(2):176-80. doi: 10.1038/6179. Nat Biotechnol. 1999. PMID: 10052355

9

Regulatable and cell-type specific transgene expression in glial cells: prospects for gene therapy for neurological disorders.

Castro M, Hurtado-Lorenzo A, Umana P, Smith-Arica JR, Zermansky A, Abordo-Adesida E, Löwenstein PR. Castro M, et al. Among authors: umana p. Prog Brain Res. 2001;132:655-81. doi: 10.1016/S0079-6123(01)32109-X. Prog Brain Res. 2001. PMID: 11545027 Review. No abstract available.

10

Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition.

Croasdale R, Wartha K, Schanzer JM, Kuenkele KP, Ries C, Mayer K, Gassner C, Wagner M, Dimoudis N, Herter S, Jaeger C, Ferrara C, Hoffmann E, Kling L, Lau W, Staack RF, Heinrich J, Scheuer W, Stracke J, Gerdes C, Brinkmann U, Umana P, Klein C. Croasdale R, et al. Among authors: umana p. Arch Biochem Biophys. 2012 Oct 15;526(2):206-18. doi: 10.1016/j.abb.2012.03.016. Epub 2012 Mar 21. Arch Biochem Biophys. 2012. PMID: 22464987

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