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Trimeric Small Interfering RNAs and Their Cholesterol-Containing Conjugates Exhibit Improved Accumulation in Tumors, but Dramatically Reduced Silencing Activity.
Molecules. 2020 Apr 18;25(8):1877. doi: 10.3390/molecules25081877.
Molecules. 2020.
PMID: 32325757
Free PMC article.
Fluorophore Labeling Affects the Cellular Accumulation and Gene Silencing Activity of Cholesterol-Modified siRNAs In Vitro.
Chernikov IV, Gladkikh DV, Meschaninova MI, Karelina UA, Ven'yaminova AG, Zenkova MA, Vlassov VV, Chernolovskaya EL.
Chernikov IV, et al. Among authors: karelina ua.
Nucleic Acid Ther. 2019 Feb;29(1):33-43. doi: 10.1089/nat.2018.0745. Epub 2018 Dec 18.
Nucleic Acid Ther. 2019.
PMID: 30562146
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