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Glucose Responsiveness of β-Cells Depends on Fatty Acids.
Gerst F, Singer C, Noack K, Graf D, Kaiser G, Panse M, Kovarova M, Schleicher E, Häring HU, Drews G, Ullrich S. Gerst F, et al. Among authors: ullrich s. Exp Clin Endocrinol Diabetes. 2020 Oct;128(10):644-653. doi: 10.1055/a-0884-2919. Epub 2019 Apr 15. Exp Clin Endocrinol Diabetes. 2020. PMID: 30986881
Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction.
Hennige AM, Ranta F, Heinzelmann I, Düfer M, Michael D, Braumüller H, Lutz SZ, Lammers R, Drews G, Bosch F, Häring HU, Ullrich S. Hennige AM, et al. Among authors: ullrich s. Diabetes. 2010 Jan;59(1):119-27. doi: 10.2337/db09-0512. Epub 2009 Oct 13. Diabetes. 2010. PMID: 19826167 Free PMC article.
Activation of extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) by free fatty acid receptor 1 (FFAR1/GPR40) protects from palmitate-induced beta cell death, but plays no role in insulin secretion.
Panse M, Gerst F, Kaiser G, Teutsch CA, Dölker R, Wagner R, Häring HU, Ullrich S. Panse M, et al. Among authors: ullrich s. Cell Physiol Biochem. 2015;35(4):1537-45. doi: 10.1159/000373969. Epub 2015 Mar 12. Cell Physiol Biochem. 2015. PMID: 25792236 Free article.
Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance.
Sabrautzki S, Kaiser G, Przemeck GKH, Gerst F, Lorza-Gil E, Panse M, Sartorius T, Hoene M, Marschall S, Häring HU, Hrabě de Angelis M, Ullrich S. Sabrautzki S, et al. Among authors: ullrich s. Mol Metab. 2017 Oct;6(10):1304-1312. doi: 10.1016/j.molmet.2017.07.007. Epub 2017 Jul 18. Mol Metab. 2017. PMID: 29031729 Free PMC article.
Human Islets Exhibit Electrical Activity on Microelectrode Arrays (MEA).
Schönecker S, Kraushaar U, Guenther E, Gerst F, Ullrich S, Häring HU, Königsrainer A, Barthlen W, Drews G, Krippeit-Drews P. Schönecker S, et al. Among authors: ullrich s. Exp Clin Endocrinol Diabetes. 2015 May;123(5):296-8. doi: 10.1055/s-0035-1547217. Epub 2015 Apr 8. Exp Clin Endocrinol Diabetes. 2015. PMID: 25853706
Mice Lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are Protected Against Conjugated Linoleic Acid-Induced Fatty Liver but Develop Inflammation and Insulin Resistance in the Brain.
Sartorius T, Drescher A, Panse M, Lastovicka P, Peter A, Weigert C, Kostenis E, Ullrich S, Häring HU. Sartorius T, et al. Among authors: ullrich s. Cell Physiol Biochem. 2015;35(6):2272-84. doi: 10.1159/000374031. Epub 2015 Apr 13. Cell Physiol Biochem. 2015. PMID: 25895678 Free article.
640 results