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Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds.
Palušová V, Renzová T, Verlande A, Vaclová T, Medková M, Cetlová L, Sedláčková M, Hříbková H, Slaninová I, Krutá M, Rotrekl V, Uhlířová H, Křížová A, Chmelík R, Veselý P, Krafčíková M, Trantírek L, Schink KO, Uldrijan S. Palušová V, et al. Among authors: uldrijan s. Cancers (Basel). 2020 Jun 10;12(6):1516. doi: 10.3390/cancers12061516. Cancers (Basel). 2020. PMID: 32531927 Free PMC article.
A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein.
Valianatos G, Valcikova B, Growkova K, Verlande A, Mlcochova J, Radova L, Stetkova M, Vyhnakova M, Slaby O, Uldrijan S. Valianatos G, et al. Among authors: uldrijan s. PLoS One. 2017 Oct 3;12(10):e0185801. doi: 10.1371/journal.pone.0185801. eCollection 2017. PLoS One. 2017. PMID: 28973015 Free PMC article.
Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization.
Verlande A, Krafčíková M, Potěšil D, Trantírek L, Zdráhal Z, Elkalaf M, Trnka J, Souček K, Rauch N, Rauch J, Kolch W, Uldrijan S. Verlande A, et al. Among authors: uldrijan s. EMBO Rep. 2018 Feb;19(2):320-336. doi: 10.15252/embr.201744524. Epub 2017 Dec 20. EMBO Rep. 2018. PMID: 29263201 Free PMC article.
CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells.
Štětková M, Growková K, Fojtík P, Valčíková B, Palušová V, Verlande A, Jorda R, Kryštof V, Hejret V, Alexiou P, Rotrekl V, Uldrijan S. Štětková M, et al. Among authors: uldrijan s. Cell Death Dis. 2020 Sep 15;11(9):754. doi: 10.1038/s41419-020-02971-3. Cell Death Dis. 2020. PMID: 32934219 Free PMC article.
29 results