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DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions.
Nat Genet. 2022 Nov;54(11):1702-1710. doi: 10.1038/s41588-022-01210-z. Epub 2022 Nov 4.
Nat Genet. 2022.
PMID: 36333500
Free PMC article.
CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci.
Chylinski K, Hubmann M, Hanna RE, Yanchus C, Michlits G, Uijttewaal ECH, Doench J, Schramek D, Elling U.
Chylinski K, et al. Among authors: uijttewaal ech.
Nat Commun. 2019 Nov 29;10(1):5454. doi: 10.1038/s41467-019-13403-y.
Nat Commun. 2019.
PMID: 31784531
Free PMC article.
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Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens.
Lopes R, Sprouffske K, Sheng C, Uijttewaal ECH, Wesdorp AE, Dahinden J, Wengert S, Diaz-Miyar J, Yildiz U, Bleu M, Apfel V, Mermet-Meillon F, Krese R, Eder M, Olsen AV, Hoppe P, Knehr J, Carbone W, Cuttat R, Waldt A, Altorfer M, Naumann U, Weischenfeldt J, deWeck A, Kauffmann A, Roma G, Schübeler D, Galli GG.
Lopes R, et al. Among authors: uijttewaal ech.
Sci Adv. 2021 Jul 2;7(27):eabf5733. doi: 10.1126/sciadv.abf5733. Print 2021 Jul.
Sci Adv. 2021.
PMID: 34215580
Free PMC article.
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Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation.
Yost S, de Wolf B, Hanks S, Zachariou A, Marcozzi C, Clarke M, de Voer R, Etemad B, Uijttewaal E, Ramsay E, Wylie H, Elliott A, Picton S, Smith A, Smithson S, Seal S, Ruark E, Houge G, Pines J, Kops GJPL, Rahman N.
Yost S, et al.
Nat Genet. 2017 Jul;49(7):1148-1151. doi: 10.1038/ng.3883. Epub 2017 May 29.
Nat Genet. 2017.
PMID: 28553959
Free PMC article.
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Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression.
Vos ESM, Valdes-Quezada C, Huang Y, Allahyar A, Verstegen MJAM, Felder AK, van der Vegt F, Uijttewaal ECH, Krijger PHL, de Laat W.
Vos ESM, et al. Among authors: uijttewaal ech.
Mol Cell. 2021 Aug 5;81(15):3082-3095.e6. doi: 10.1016/j.molcel.2021.06.008. Epub 2021 Jun 30.
Mol Cell. 2021.
PMID: 34197738
Free article.
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Chromosomal instability by mutations in the novel minor spliceosome component CENATAC.
de Wolf B, Oghabian A, Akinyi MV, Hanks S, Tromer EC, van Hooff JJE, van Voorthuijsen L, van Rooijen LE, Verbeeren J, Uijttewaal ECH, Baltissen MPA, Yost S, Piloquet P, Vermeulen M, Snel B, Isidor B, Rahman N, Frilander MJ, Kops GJPL.
de Wolf B, et al. Among authors: uijttewaal ech.
EMBO J. 2021 Jul 15;40(14):e106536. doi: 10.15252/embj.2020106536. Epub 2021 May 19.
EMBO J. 2021.
PMID: 34009673
Free PMC article.
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