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A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity.
Koch K, Hartmann R, Tsiampali J, Uhlmann C, Nickel AC, He X, Kamp MA, Sabel M, Barker RA, Steiger HJ, Hänggi D, Willbold D, Maciaczyk J, Kahlert UD. Koch K, et al. Among authors: uhlmann c. Cell Death Discov. 2020 Apr 16;6:20. doi: 10.1038/s41420-020-0258-3. eCollection 2020. Cell Death Discov. 2020. PMID: 32337072 Free PMC article.
Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro.
Suwala AK, Koch K, Rios DH, Aretz P, Uhlmann C, Ogorek I, Felsberg J, Reifenberger G, Köhrer K, Deenen R, Steiger HJ, Kahlert UD, Maciaczyk J. Suwala AK, et al. Among authors: uhlmann c. Oncotarget. 2018 Apr 27;9(32):22703-22716. doi: 10.18632/oncotarget.25210. eCollection 2018 Apr 27. Oncotarget. 2018. PMID: 29854309 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33563939
Progenitor cells derived from gene-engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology.
Uhlmann C, Nickel AC, Picard D, Rossi A, Li G, Hildebrandt B, Brockerhoff G, Bendt F, Hübenthal U, Hewera M, Steiger HJ, Wieczorek D, Perrakis A, Zhang W, Remke M, Koch K, Tigges J, Croner RS, Fritsche E, Kahlert UD. Uhlmann C, et al. Biotechnol J. 2022 Jun;17(6):e2100693. doi: 10.1002/biot.202100693. Epub 2022 Apr 3. Biotechnol J. 2022. PMID: 35334498
The development of a hiPSC-based platform to identify tissue-dependencies of IDH1 R132H.
Mehjardi NZ, Kessler J, Sanin AY, Picard D, Westhoff P, Nickel AC, Uhlmann C, Shi W, Steiger HJ, Remke M, Fischer I, Vordermark D, Croner RS, Kahlert UD. Mehjardi NZ, et al. Among authors: uhlmann c. Cell Death Discov. 2023 Dec 12;9(1):452. doi: 10.1038/s41420-023-01747-w. Cell Death Discov. 2023. PMID: 38086797 Free PMC article.
Cycloheptatrienyl-Bridged Triple-Decker Complexes.
Hauser A, Münzfeld L, Schlittenhardt S, Uhlmann C, Leyen L, Moreno-Pineda E, Ruben M, Roesky PW. Hauser A, et al. Among authors: uhlmann c. J Am Chem Soc. 2024 May 8. doi: 10.1021/jacs.3c12214. Online ahead of print. J Am Chem Soc. 2024. PMID: 38718186
86 results