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A miR-29a-driven negative feedback loop regulates peripheral glucocorticoid receptor signaling.
Glantschnig C, Koenen M, Gil-Lozano M, Karbiener M, Pickrahn I, Williams-Dautovich J, Patel R, Cummins CL, Giroud M, Hartleben G, Vogl E, Blüher M, Tuckermann J, Uhlenhaut H, Herzig S, Scheideler M. Glantschnig C, et al. Among authors: uhlenhaut h. FASEB J. 2019 May;33(5):5924-5941. doi: 10.1096/fj.201801385RR. Epub 2019 Feb 11. FASEB J. 2019. PMID: 30742779
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD. Fischer K, et al. Among authors: uhlenhaut h. Nat Commun. 2020 May 8;11(1):2306. doi: 10.1038/s41467-020-16230-8. Nat Commun. 2020. PMID: 32385399 Free PMC article.
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
Giroud M, Tsokanos FF, Caratti G, Kotschi S, Khani S, Jouffe C, Vogl ES, Irmler M, Glantschnig C, Gil-Lozano M, Hass D, Khan AA, Garcia MR, Mattijssen F, Maida A, Tews D, Fischer-Posovszky P, Feuchtinger A, Virtanen KA, Beckers J, Wabitsch M, Uhlenhaut H, Blüher M, Tuckermann J, Scheideler M, Bartelt A, Herzig S. Giroud M, et al. Among authors: uhlenhaut h. Diabetologia. 2021 Aug;64(8):1850-1865. doi: 10.1007/s00125-021-05470-y. Epub 2021 May 20. Diabetologia. 2021. PMID: 34014371 Free PMC article.
ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.
Fougerat A, Schoiswohl G, Polizzi A, Régnier M, Wagner C, Smati S, Fougeray T, Lippi Y, Lasserre F, Raho I, Melin V, Tramunt B, Métivier R, Sommer C, Benhamed F, Alkhoury C, Greulich F, Jouffe C, Emile A, Schupp M, Gourdy P, Dubot P, Levade T, Meynard D, Ellero-Simatos S, Gamet-Payrastre L, Panasyuk G, Uhlenhaut H, Amri EZ, Cruciani-Guglielmacci C, Postic C, Wahli W, Loiseau N, Montagner A, Langin D, Lass A, Guillou H. Fougerat A, et al. Among authors: uhlenhaut h. Cell Rep. 2022 Jun 7;39(10):110910. doi: 10.1016/j.celrep.2022.110910. Cell Rep. 2022. PMID: 35675775 Free article.
Exercise-dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF-SRF signalling.
Solagna F, Nogara L, Dyar KA, Greulich F, Mir AA, Türk C, Bock T, Geremia A, Baraldo M, Sartori R, Farup J, Uhlenhaut H, Vissing K, Krüger M, Blaauw B. Solagna F, et al. Among authors: uhlenhaut h. Acta Physiol (Oxf). 2020 Sep;230(1):e13496. doi: 10.1111/apha.13496. Epub 2020 May 30. Acta Physiol (Oxf). 2020. PMID: 32408395 Free PMC article.
Mineralocorticoid receptors in non-alcoholic fatty liver disease.
Schreier B, Zipprich A, Uhlenhaut H, Gekle M. Schreier B, et al. Among authors: uhlenhaut h. Br J Pharmacol. 2022 Jul;179(13):3165-3177. doi: 10.1111/bph.15784. Epub 2022 Feb 4. Br J Pharmacol. 2022. PMID: 34935140 Free article. Review.
Ventilator-induced Lung Injury Is Modulated by the Circadian Clock.
Felten M, Ferencik S, Teixeira Alves LG, Letsiou E, Lienau J, Müller-Redetzky HC, Langenhagen AK, Voß A, Dietert K, Kershaw O, Gruber AD, Michalick L, Kuebler WM, Ananthasubramaniam B, Maier B, Uhlenhaut H, Kramer A, Witzenrath M. Felten M, et al. Among authors: uhlenhaut h. Am J Respir Crit Care Med. 2023 Jun 1;207(11):1464-1474. doi: 10.1164/rccm.202202-0320OC. Am J Respir Crit Care Med. 2023. PMID: 36480958