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Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance.
Biol Open. 2018 Jul 23;7(7):bio036103. doi: 10.1242/bio.036103.
Biol Open. 2018.
PMID: 30037883
Free PMC article.
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Cr…
See abstract for full author list ➔
Gordon DE, et al. Among authors: ugur fs.
Nature. 2020 Jul;583(7816):459-468. doi: 10.1038/s41586-020-2286-9. Epub 2020 Apr 30.
Nature. 2020.
PMID: 32353859
Free PMC article.
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Chromatin Sensing by the Auxiliary Domains of KDM5C Regulates Its Demethylase Activity and Is Disrupted by X-linked Intellectual Disability Mutations.
Ugur FS, Kelly MJS, Fujimori DG.
Ugur FS, et al.
J Mol Biol. 2023 Jan 30;435(2):167913. doi: 10.1016/j.jmb.2022.167913. Epub 2022 Dec 7.
J Mol Biol. 2023.
PMID: 36495919
Free PMC article.
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Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3.
Anderson SE, Longbotham JE, O'Kane PT, Ugur FS, Fujimori DG, Mrksich M.
Anderson SE, et al. Among authors: ugur fs.
ACS Chem Biol. 2021 Jan 15;16(1):205-213. doi: 10.1021/acschembio.0c00891. Epub 2020 Dec 14.
ACS Chem Biol. 2021.
PMID: 33314922
Free PMC article.
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Source of the Fitness Defect in Rifamycin-Resistant Mycobacterium tuberculosis RNA Polymerase and the Mechanism of Compensation by Mutations in the β' Subunit.
Stefan MA, Ugur FS, Garcia GA.
Stefan MA, et al. Among authors: ugur fs.
Antimicrob Agents Chemother. 2018 May 25;62(6):e00164-18. doi: 10.1128/AAC.00164-18. Print 2018 Jun.
Antimicrob Agents Chemother. 2018.
PMID: 29661864
Free PMC article.
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Successful cryoablation of atrioventricular nodal reentrant tachycardia and coexisting accessory pathways without fluoroscopy.
Gul EE, Ugur FS, Akdeniz C, Tuzcu V.
Gul EE, et al. Among authors: ugur fs.
Congenit Heart Dis. 2013 Nov-Dec;8(6):E178-82. doi: 10.1111/chd.12029. Epub 2012 Dec 27.
Congenit Heart Dis. 2013.
PMID: 23280143
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