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New derivatives from dehydrodieugenol B and its methyl ether displayed high anti-Trypanosoma cruzi activity and cause depolarization of the plasma membrane and collapse the mitochondrial membrane potential.
Chem Biol Interact. 2022 Oct 1;366:110129. doi: 10.1016/j.cbi.2022.110129. Epub 2022 Sep 5.
Chem Biol Interact. 2022.
PMID: 36067825
Free article.
Gibbilimbol analogues as antiparasitic agents--Synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum.
Varela MT, Dias RZ, Martins LF, Ferreira DD, Tempone AG, Ueno AK, Lago JH, Fernandes JP.
Varela MT, et al. Among authors: ueno ak.
Bioorg Med Chem Lett. 2016 Feb 15;26(4):1180-3. doi: 10.1016/j.bmcl.2016.01.040. Epub 2016 Jan 16.
Bioorg Med Chem Lett. 2016.
PMID: 26821820
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Antitrypanosomal activity and evaluation of the mechanism of action of diterpenes from aerial parts of Baccharis retusa (Asteraceae).
Ueno AK, Barcellos AF, Costa-Silva TA, Mesquita JT, Ferreira DD, Tempone AG, Romoff P, Antar GM, Lago JHG.
Ueno AK, et al.
Fitoterapia. 2018 Mar;125:55-58. doi: 10.1016/j.fitote.2017.12.016. Epub 2017 Dec 18.
Fitoterapia. 2018.
PMID: 29269235
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Highly selective alkylcoumarates and diterpenoids isolated from leaves of Baccharis quitensis: a search for new hit compounds against Trypanosoma cruzi.
Peres N, Silva ML, Ueno AK, Antar GM, Levatti EVC, Tempone AG, Lago JHG.
Peres N, et al. Among authors: ueno ak.
Nat Prod Res. 2024 Mar 27:1-7. doi: 10.1080/14786419.2024.2335362. Online ahead of print.
Nat Prod Res. 2024.
PMID: 38538549
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Sakuranetin exerts anticonvulsant effect in bicuculline-induced seizures.
Vicente-Silva W, Silva-Freitas FR, Beserra-Filho JIA, Cardoso GN, Silva-Martins S, Sarno TA, Silva SP, Soares-Silva B, Dos Santos JR, da Silva RH, Prado CM, Ueno AK, Lago JHG, Ribeiro AM.
Vicente-Silva W, et al. Among authors: ueno ak.
Fundam Clin Pharmacol. 2022 Aug;36(4):663-673. doi: 10.1111/fcp.12768. Epub 2022 Feb 21.
Fundam Clin Pharmacol. 2022.
PMID: 35156229
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