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Electrolyzed hypochlorous acid water exhibits potent disinfectant activity against various viruses through irreversible protein aggregation.
Dianty R, Hirano J, Anzai I, Kanai Y, Hayashi T, Morimoto M, Kataoka-Nakamura C, Kobayashi S, Uemura K, Ono C, Watanabe T, Kobayashi T, Murakami K, Kikuchi K, Hotta K, Yoshikawa T, Taguwa S, Matsuura Y. Dianty R, et al. Among authors: uemura k. Front Microbiol. 2023 Oct 19;14:1284274. doi: 10.3389/fmicb.2023.1284274. eCollection 2023. Front Microbiol. 2023. PMID: 37928667 Free PMC article.
Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus.
Yamamoto S, Fukuhara T, Ono C, Uemura K, Kawachi Y, Shiokawa M, Mori H, Wada M, Shima R, Okamoto T, Hiraga N, Suzuki R, Chayama K, Wakita T, Matsuura Y. Yamamoto S, et al. Among authors: uemura k. PLoS Pathog. 2016 May 6;12(5):e1005610. doi: 10.1371/journal.ppat.1005610. eCollection 2016 May. PLoS Pathog. 2016. PMID: 27152966 Free PMC article.
Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae.
Fukuhara T, Tamura T, Ono C, Shiokawa M, Mori H, Uemura K, Yamamoto S, Kurihara T, Okamoto T, Suzuki R, Yoshii K, Kurosu T, Igarashi M, Aoki H, Sakoda Y, Matsuura Y. Fukuhara T, et al. Among authors: uemura k. PLoS Pathog. 2017 Jun 23;13(6):e1006475. doi: 10.1371/journal.ppat.1006475. eCollection 2017 Jun. PLoS Pathog. 2017. PMID: 28644867 Free PMC article.
Characterization of miR-122-independent propagation of HCV.
Ono C, Fukuhara T, Motooka D, Nakamura S, Okuzaki D, Yamamoto S, Tamura T, Mori H, Sato A, Uemura K, Fauzyah Y, Kurihara T, Suda T, Nishio A, Hmwe SS, Okamoto T, Tatsumi T, Takehara T, Chayama K, Wakita T, Koike K, Matsuura Y. Ono C, et al. Among authors: uemura k. PLoS Pathog. 2017 May 11;13(5):e1006374. doi: 10.1371/journal.ppat.1006374. eCollection 2017 May. PLoS Pathog. 2017. PMID: 28494029 Free PMC article.
2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses.
Uemura K, Nobori H, Sato A, Toba S, Kusakabe S, Sasaki M, Tabata K, Matsuno K, Maeda N, Ito S, Tanaka M, Anraku Y, Kita S, Ishii M, Kanamitsu K, Orba Y, Matsuura Y, Hall WW, Sawa H, Kida H, Matsuda A, Maenaka K. Uemura K, et al. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2304139120. doi: 10.1073/pnas.2304139120. Epub 2023 Oct 13. Proc Natl Acad Sci U S A. 2023. PMID: 37831739 Free PMC article.
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H. Sasaki M, et al. Among authors: uemura k. Sci Transl Med. 2023 Jan 18;15(679):eabq4064. doi: 10.1126/scitranslmed.abq4064. Epub 2023 Jan 18. Sci Transl Med. 2023. PMID: 36327352 Free PMC article.
1,786 results