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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 2
2002 5
2003 6
2004 9
2005 7
2006 9
2007 7
2008 7
2009 7
2010 6
2011 7
2012 8
2013 4
2014 4
2015 2
2016 5
2017 6
2018 4
2019 5
2020 4
2021 5
2022 2
2023 4
2024 1

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117 results

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Page 1
Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors.
Specker E, Wesolowski R, Schütz A, Matthes S, Mallow K, Wasinska-Kalwa M, Winkler L, Oder A, Alenina N, Pleimes D, von Kries JP, Heinemann U, Bader M, Nazaré M. Specker E, et al. Among authors: heinemann u. J Med Chem. 2023 Nov 9;66(21):14866-14896. doi: 10.1021/acs.jmedchem.3c01454. Epub 2023 Oct 31. J Med Chem. 2023. PMID: 37905925
TapA acts as specific chaperone in TasA filament formation by strand complementation.
Roske Y, Lindemann F, Diehl A, Cremer N, Higman VA, Schlegel B, Leidert M, Driller K, Turgay K, Schmieder P, Heinemann U, Oschkinat H. Roske Y, et al. Among authors: heinemann u. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2217070120. doi: 10.1073/pnas.2217070120. Epub 2023 Apr 17. Proc Natl Acad Sci U S A. 2023. PMID: 37068239 Free PMC article.
Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors.
Specker E, Matthes S, Wesolowski R, Schütz A, Grohmann M, Alenina N, Pleimes D, Mallow K, Neuenschwander M, Gogolin A, Weise M, Pfeifer J, Ziebart N, Heinemann U, von Kries JP, Nazaré M, Bader M. Specker E, et al. Among authors: heinemann u. J Med Chem. 2022 Aug 25;65(16):11126-11149. doi: 10.1021/acs.jmedchem.2c00598. Epub 2022 Aug 3. J Med Chem. 2022. PMID: 35921615
An Integrated Pharmacological, Structural, and Genetic Analysis of Extracellular Versus Intracellular ROS Production in Neutrophils.
Ellson CD, Riça IG, Kim JS, Huang YM, Lim D, Mitra T, Hsu A, Wei EX, Barrett CD, Otterbein LE, Hauser CJ, Wahl M, Delbrück H, Heinemann U, Oschkinat H, Chang CA, Yaffe MB. Ellson CD, et al. Among authors: heinemann u. J Mol Biol. 2022 May 15;434(9):167533. doi: 10.1016/j.jmb.2022.167533. Epub 2022 Mar 18. J Mol Biol. 2022. PMID: 35314146
Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer.
Carter DM, Specker E, Małecki PH, Przygodda J, Dudaniec K, Weiss MS, Heinemann U, Nazaré M, Gohlke U. Carter DM, et al. Among authors: heinemann u. J Med Chem. 2021 Oct 14;64(19):14266-14282. doi: 10.1021/acs.jmedchem.1c00693. Epub 2021 Sep 23. J Med Chem. 2021. PMID: 34555281 Free article.
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.
Kamdem N, Roske Y, Kovalskyy D, Platonov MO, Balinskyi O, Kreuchwig A, Saupe J, Fang L, Diehl A, Schmieder P, Krause G, Rademann J, Heinemann U, Birchmeier W, Oschkinat H. Kamdem N, et al. Among authors: heinemann u. Magn Reson (Gott). 2021 Jun 2;2(1):355-374. doi: 10.5194/mr-2-355-2021. eCollection 2021. Magn Reson (Gott). 2021. PMID: 37904770 Free PMC article.
117 results