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Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases.
Shuto T, Kamei S, Nohara H, Fujikawa H, Tasaki Y, Sugahara T, Ono T, Matsumoto C, Sakaguchi Y, Maruta K, Nakashima R, Kawakami T, Suico MA, Kondo Y, Ishigami A, Takeo T, Tanaka KI, Watanabe H, Nakagata N, Uchimura K, Kitamura K, Li JD, Kai H. Shuto T, et al. Among authors: uchimura k. Sci Rep. 2016 Dec 16;6:39305. doi: 10.1038/srep39305. Sci Rep. 2016. PMID: 27982104 Free PMC article.
Regulation of adrenal aldosterone production by serine protease prostasin.
Ko T, Kakizoe Y, Wakida N, Hayata M, Uchimura K, Shiraishi N, Miyoshi T, Adachi M, Aritomi S, Konda T, Tomita K, Kitamura K. Ko T, et al. Among authors: uchimura k. J Biomed Biotechnol. 2010;2010:793843. doi: 10.1155/2010/793843. Epub 2010 Mar 2. J Biomed Biotechnol. 2010. PMID: 20204133 Free PMC article.
Effect of a serine protease inhibitor on the progression of chronic renal failure.
Hayata M, Kakizoe Y, Uchimura K, Morinaga J, Yamazoe R, Mizumoto T, Onoue T, Ueda M, Shiraishi N, Adachi M, Miyoshi T, Sakai Y, Tomita K, Kitamura K. Hayata M, et al. Among authors: uchimura k. Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1126-35. doi: 10.1152/ajprenal.00706.2011. Epub 2012 Jul 25. Am J Physiol Renal Physiol. 2012. PMID: 22832926 Free article.
The antifibrotic effect of a serine protease inhibitor in the kidney.
Morinaga J, Kakizoe Y, Miyoshi T, Onoue T, Ueda M, Mizumoto T, Yamazoe R, Uchimura K, Hayata M, Shiraishi N, Adachi M, Sakai Y, Tomita K, Kitamura K. Morinaga J, et al. Among authors: uchimura k. Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F173-81. doi: 10.1152/ajprenal.00586.2012. Epub 2013 May 22. Am J Physiol Renal Physiol. 2013. PMID: 23698112 Free article.
Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.
Narita Y, Ueda M, Uchimura K, Kakizoe Y, Miyasato Y, Mizumoto T, Morinaga J, Hayata M, Nakagawa T, Adachi M, Miyoshi T, Sakai Y, Kadowaki D, Hirata S, Mukoyama M, Kitamura K. Narita Y, et al. Among authors: uchimura k. J Pharmacol Sci. 2016 Feb;130(2):110-6. doi: 10.1016/j.jphs.2016.01.003. Epub 2016 Jan 20. J Pharmacol Sci. 2016. PMID: 26887332 Free article.
A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity.
Kakizoe Y, Miyasato Y, Onoue T, Nakagawa T, Hayata M, Uchimura K, Morinaga J, Mizumoto T, Adachi M, Miyoshi T, Sakai Y, Tomita K, Mukoyama M, Kitamura K. Kakizoe Y, et al. Among authors: uchimura k. J Pharmacol Sci. 2016 Oct;132(2):145-153. doi: 10.1016/j.jphs.2016.09.005. Epub 2016 Sep 30. J Pharmacol Sci. 2016. PMID: 27773435 Free article.
A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats.
Mizumoto T, Kakizoe Y, Nakagawa T, Iwata Y, Miyasato Y, Uchimura K, Adachi M, Deng Q, Hayata M, Morinaga J, Miyoshi T, Izumi Y, Kuwabara T, Sakai Y, Tomita K, Kitamura K, Mukoyama M. Mizumoto T, et al. Among authors: uchimura k. J Pharmacol Sci. 2021 Aug;146(4):192-199. doi: 10.1016/j.jphs.2021.04.003. Epub 2021 Apr 24. J Pharmacol Sci. 2021. PMID: 34116732 Free article.
337 results