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Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer.
Buikhuisen JY, Gomez Barila PM, Cameron K, Suijkerbuijk SJE, Lieftink C, di Franco S, Krotenberg Garcia A, Uceda Castro R, Lenos KJ, Nijman LE, Torang A, Longobardi C, de Jong JH, Dekker D, Stassi G, Vermeulen L, Beijersbergen RL, van Rheenen J, Huveneers S, Medema JP. Buikhuisen JY, et al. Among authors: uceda castro r. J Exp Clin Cancer Res. 2023 Mar 3;42(1):56. doi: 10.1186/s13046-023-02600-9. J Exp Clin Cancer Res. 2023. PMID: 36869386 Free PMC article.
Epithelial-to-Mesenchymal Transition Drives Invasiveness of Breast Cancer Brain Metastases.
Margarido AS, Uceda-Castro R, Hahn K, de Bruijn R, Kester L, Hofland I, Lohuis J, Seinstra D, Broeks A, Jonkers J, Broekman MLD, Wesseling P, Vennin C, Vizoso M, van Rheenen J. Margarido AS, et al. Among authors: uceda castro r. Cancers (Basel). 2022 Jun 25;14(13):3115. doi: 10.3390/cancers14133115. Cancers (Basel). 2022. PMID: 35804890 Free PMC article.
BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis.
Uceda-Castro R, Margarido AS, Song JY, de Gooijer MC, Messal HA, Chambers CR, Nobis M, Çitirikkaya CH, Hahn K, Seinstra D, Herrmann D, Timpson P, Wesseling P, van Tellingen O, Vennin C, van Rheenen J. Uceda-Castro R, et al. Sci Adv. 2023 Oct 20;9(42):eabp9530. doi: 10.1126/sciadv.abp9530. Epub 2023 Oct 18. Sci Adv. 2023. PMID: 37851804 Free PMC article.
Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.
Uceda-Castro R, Margarido AS, Cornet L, Vegna S, Hahn K, Song JY, Putavet DA, van Geldorp M, Çitirikkaya CH, de Keizer PLJ, Ter Beek LC, Borst GR, Akkari L, van Tellingen O, Broekman MLD, Vennin C, van Rheenen J. Uceda-Castro R, et al. Cell Rep Med. 2022 Nov 15;3(11):100821. doi: 10.1016/j.xcrm.2022.100821. Cell Rep Med. 2022. PMID: 36384097 Free PMC article.
Matrix metalloproteinase-9 induces a pro-angiogenic profile in chronic lymphocytic leukemia cells.
Aguilera-Montilla N, Bailón E, Ugarte-Berzal E, Uceda-Castro R, Prieto-Solano M, García-Martínez E, Samaniego R, Van den Steen PE, Opdenakker G, García-Marco JA, García-Pardo A. Aguilera-Montilla N, et al. Among authors: uceda castro r. Biochem Biophys Res Commun. 2019 Nov 26;520(1):198-204. doi: 10.1016/j.bbrc.2019.09.127. Epub 2019 Oct 1. Biochem Biophys Res Commun. 2019. PMID: 31585732 Free article.
MMP-9 affects gene expression in chronic lymphocytic leukemia revealing CD99 as an MMP-9 target and a novel partner in malignant cell migration/arrest.
Aguilera-Montilla N, Bailón E, Uceda-Castro R, Ugarte-Berzal E, Santos A, Gutiérrez-González A, Pérez-Sánchez C, Van den Steen PE, Opdenakker G, García-Marco JA, García-Pardo A. Aguilera-Montilla N, et al. Among authors: uceda castro r. Oncogene. 2019 Jun;38(23):4605-4619. doi: 10.1038/s41388-019-0744-3. Epub 2019 Feb 13. Oncogene. 2019. PMID: 30760844 Free article.