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2021 2
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2024 6

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Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to an integrase inhibitor based antiretroviral regimen.
Ferreira RC, Reynolds SJ, Capoferri AA, Baker OR, Brown EE, Klock E, Miller J, Lai J, Saraf S, Kirby C, Lynch B, Hackman J, Gowanlock SN, Tomusange S, Jamiru S, Anok A, Kityamuweesi T, Buule P, Bruno D, Martens C, Rose R, Lamers SL, Galiwango RM, Poon AFY, Quinn TC, Prodger JL, Redd AD. Ferreira RC, et al. EBioMedicine. 2024 Apr;102:105040. doi: 10.1016/j.ebiom.2024.105040. Epub 2024 Mar 13. EBioMedicine. 2024. PMID: 38485563 Free PMC article.
Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques.
Lim SY, Lee J, Osuna CE, Vikhe P, Schalk DR, Chen E, Fray E, Kumar M, Schultz-Darken N, Rakasz E, Capuano S, Ladd RA, Gil HM, Evans DT, Jeng EK, Seaman M, Martin M, Van Dorp C, Perelson AS, Wong HC, Siliciano JD, Siliciano R, Safrit JT, Nixon DF, Soon-Shiong P, Nussenzweig M, Whitney JB. Lim SY, et al. Science. 2024 Mar 8;383(6687):1104-1111. doi: 10.1126/science.adf7966. Epub 2024 Feb 29. Science. 2024. PMID: 38422185 Free PMC article.
Effects of COVID-19 mRNA vaccination on HIV viremia and reservoir size.
Duncan MC, Omondi FH, Kinloch NN, Lapointe HR, Speckmaier S, Moran-Garcia N, Lawson T, DeMarco ML, Simons J, Holmes DT, Lowe CF, Bacani N, Sereda P, Barrios R, Harris M, Romney MG, Montaner JSG, Brumme CJ, Brockman MA, Brumme ZL. Duncan MC, et al. AIDS. 2024 Jan 15. doi: 10.1097/QAD.0000000000003841. Online ahead of print. AIDS. 2024. PMID: 38224350
The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over time.
Shahid A, MacLennan S, Jones BR, Sudderuddin H, Dang Z, Cobarrubias K, Duncan MC, Kinloch NN, Dapp MJ, Archin NM, Fischl MA, Ofotokun I, Adimora A, Gange S, Aouizerat B, Kuniholm MH, Kassaye S, Mullins JI, Goldstein H, Joy JB, Anastos K, Brumme ZL; MACS/WIHS combined cohort study (MWCSS). Shahid A, et al. J Virol. 2024 Feb 20;98(2):e0165523. doi: 10.1128/jvi.01655-23. Epub 2024 Jan 12. J Virol. 2024. PMID: 38214547 Free PMC article.
Harnessing immune cells to eliminate HIV reservoirs.
Grasberger P, Sondrini AR, Clayton KL. Grasberger P, et al. Curr Opin HIV AIDS. 2024 Mar 1;19(2):62-68. doi: 10.1097/COH.0000000000000840. Epub 2024 Jan 2. Curr Opin HIV AIDS. 2024. PMID: 38167784 Review.
3D human tissue models and microphysiological systems for HIV and related comorbidities.
3D Human Tissue Models for HIV Working Group. Electronic address: dwight.yin@nih.gov; 3D Human Tissue Models for HIV Working Group. 3D Human Tissue Models for HIV Working Group. Electronic address: dwight.yin@nih.gov, et al. Trends Biotechnol. 2024 May;42(5):526-543. doi: 10.1016/j.tibtech.2023.10.008. Epub 2023 Dec 8. Trends Biotechnol. 2024. PMID: 38071144 Review.
HIV reservoirs are dominated by genetically younger and clonally enriched proviruses.
Kinloch NN, Shahid A, Dong W, Kirkby D, Jones BR, Beelen CJ, MacMillan D, Lee GQ, Mota TM, Sudderuddin H, Barad E, Harris M, Brumme CJ, Jones RB, Brockman MA, Joy JB, Brumme ZL. Kinloch NN, et al. mBio. 2023 Nov 16;14(6):e0241723. doi: 10.1128/mbio.02417-23. Online ahead of print. mBio. 2023. PMID: 37971267 Free PMC article.
Effects of COVID-19 mRNA vaccination on HIV viremia and reservoir size.
Duncan MC, Omondi FH, Kinloch NN, Lapointe HR, Speckmaier S, Moran-Garcia N, Lawson T, DeMarco ML, Simons J, Holmes DT, Lowe CF, Bacani N, Sereda P, Barrios R, Harris M, Romney MG, Montaner JSG, Brumme CJ, Brockman MA, Brumme ZL. Duncan MC, et al. medRxiv [Preprint]. 2023 Oct 9:2023.10.08.23296718. doi: 10.1101/2023.10.08.23296718. medRxiv. 2023. PMID: 37873490 Free PMC article. Updated. Preprint.
52 results