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2021 3
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Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis.
Amadori L, Calcagno C, Fernandez DM, Koplev S, Fernandez N, Kaur R, Mury P, Khan NS, Sajja S, Shamailova R, Cyr Y, Jeon M, Hill CA, Chong PS, Naidu S, Sakurai K, Ghotbi AA, Soler R, Eberhardt N, Rahman A, Faries P, Moore KJ, Fayad ZA, Ma'ayan A, Giannarelli C. Amadori L, et al. Nat Cardiovasc Res. 2023 Jun;2(6):550-571. doi: 10.1038/s44161-023-00278-y. Epub 2023 Jun 8. Nat Cardiovasc Res. 2023. PMID: 37771373 Free PMC article.
Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling.
Canfrán-Duque A, Rotllan N, Zhang X, Andrés-Blasco I, Thompson BM, Sun J, Price NL, Fernández-Fuertes M, Fowler JW, Gómez-Coronado D, Sessa WC, Giannarelli C, Schneider RJ, Tellides G, McDonald JG, Fernández-Hernando C, Suárez Y. Canfrán-Duque A, et al. Circulation. 2023 Jan 31;147(5):388-408. doi: 10.1161/CIRCULATIONAHA.122.059062. Epub 2022 Nov 23. Circulation. 2023. PMID: 36416142 Free PMC article.
Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation.
Toner YC, Ghotbi AA, Naidu S, Sakurai K, van Leent MMT, Jordan S, Ordikhani F, Amadori L, Sofias AM, Fisher EL, Maier A, Sullivan N, Munitz J, Senders ML, Mason C, Reiner T, Soultanidis G, Tarkin JM, Rudd JHF, Giannarelli C, Ochando J, Pérez-Medina C, Kjaer A, Mulder WJM, Fayad ZA, Calcagno C. Toner YC, et al. Sci Rep. 2022 Apr 13;12(1):6185. doi: 10.1038/s41598-022-09590-2. Sci Rep. 2022. PMID: 35418569 Free PMC article.
Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis.
Weinstock A, Rahman K, Yaacov O, Nishi H, Menon P, Nikain CA, Garabedian ML, Pena S, Akbar N, Sansbury BE, Heffron SP, Liu J, Marecki G, Fernandez D, Brown EJ, Ruggles KV, Ramsey SA, Giannarelli C, Spite M, Choudhury RP, Loke P, Fisher EA. Weinstock A, et al. Elife. 2021 Mar 15;10:e67932. doi: 10.7554/eLife.67932. Elife. 2021. PMID: 33720008 Free PMC article.