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Pharmacokinetic and Pharmacodynamic Consequences of Cytochrome P450 3A Inhibition on Mitragynine Metabolism in Rats.
Kamble SH, Obeng S, León F, Restrepo LF, King TI, Berthold EC, Kanumuri SRR, Gamez-Jimenez LR, Pallares VLC, Patel A, Ho NP, Hampson A, McCurdy CR, McMahon LR, Wilkerson JL, Sharma A, Hiranita T. Kamble SH, et al. J Pharmacol Exp Ther. 2023 Jun;385(3):180-192. doi: 10.1124/jpet.122.001525. Epub 2023 Apr 5. J Pharmacol Exp Ther. 2023. PMID: 37019472 Free PMC article.
Kratom Alkaloids: A Blueprint?
Smith KE, Sharma A, Grundmann O, McCurdy CR. Smith KE, et al. ACS Chem Neurosci. 2023 Jan 18;14(2):195-197. doi: 10.1021/acschemneuro.2c00704. Epub 2023 Jan 3. ACS Chem Neurosci. 2023. PMID: 36594896 Free PMC article.
The Lack of Contribution of 7-Hydroxymitragynine to the Antinociceptive Effects of Mitragynine in Mice: A Pharmacokinetic and Pharmacodynamic Study.
Berthold EC, Kamble SH, Raju KS, Kuntz MA, Senetra AS, Mottinelli M, León F, Restrepo LF, Patel A, Ho NP, Hiranita T, Sharma A, McMahon LR, McCurdy CR. Berthold EC, et al. Drug Metab Dispos. 2022 Feb;50(2):158-167. doi: 10.1124/dmd.121.000640. Epub 2021 Nov 10. Drug Metab Dispos. 2022. PMID: 34759012 Free PMC article.
17 results