UH2 TR001373/TR/NCATS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	2
2017	5
2018	4
2019	1
2023	1
2024	0

1

Phase 1 study of belinostat and adavosertib in patients with relapsed or refractory myeloid malignancies.

Shafer D, Kagan AB, Rudek MA, Kmieciak M, Tombes MB, Shrader E, Bandyopadhyay D, Hudson D, Sankala H, Weir C, Lancet JE, Grant S. Shafer D, et al. Cancer Chemother Pharmacol. 2023 Mar;91(3):281-290. doi: 10.1007/s00280-023-04511-0. Epub 2023 Mar 2. Cancer Chemother Pharmacol. 2023. PMID: 36864346 Free PMC article. Clinical Trial.

2

The Covalent CDK7 Inhibitor THZ1 Potently Induces Apoptosis in Multiple Myeloma Cells In Vitro and In Vivo.

Zhang Y, Zhou L, Bandyopadhyay D, Sharma K, Allen AJ, Kmieciak M, Grant S. Zhang Y, et al. Clin Cancer Res. 2019 Oct 15;25(20):6195-6205. doi: 10.1158/1078-0432.CCR-18-3788. Epub 2019 Jul 29. Clin Cancer Res. 2019. PMID: 31358538 Free PMC article.

3

A Phase II Trial of Bortezomib and Vorinostat in Mantle Cell Lymphoma and Diffuse Large B-cell Lymphoma.

Yazbeck V, Shafer D, Perkins EB, Coppola D, Sokol L, Richards KL, Shea T, Ruan J, Parekh S, Strair R, Flowers C, Morgan D, Kmieciak M, Bose P, Kimball A, Badros AZ, Baz R, Lin HY, Zhao X, Reich RR, Tombes MB, Shrader E, Sankala H, Roberts JD, Sullivan D, Grant S, Holkova B. Yazbeck V, et al. Clin Lymphoma Myeloma Leuk. 2018 Sep;18(9):569-575.e1. doi: 10.1016/j.clml.2018.05.023. Epub 2018 Jun 6. Clin Lymphoma Myeloma Leuk. 2018. PMID: 30122201 Clinical Trial.

4

Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells.

Rahmani M, Nkwocha J, Hawkins E, Pei X, Parker RE, Kmieciak M, Leverson JD, Sampath D, Ferreira-Gonzalez A, Grant S. Rahmani M, et al. Cancer Res. 2018 Jun 1;78(11):3075-3086. doi: 10.1158/0008-5472.CAN-17-3024. Epub 2018 Mar 20. Cancer Res. 2018. PMID: 29559471 Free PMC article.

5

A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy.

Bryant KG, Chae YC, Martinez RL, Gordon JC, Elokely KM, Kossenkov AV, Grant S, Childers WE, Abou-Gharbia M, Altieri DC. Bryant KG, et al. Oncotarget. 2017 Dec 11;8(68):112184-112198. doi: 10.18632/oncotarget.23097. eCollection 2017 Dec 22. Oncotarget. 2017. PMID: 29348817 Free PMC article.

6

Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo.

Zhou L, Zhang Y, Sampath D, Leverson J, Dai Y, Kmieciak M, Nguyen M, Orlowski RZ, Grant S. Zhou L, et al. Br J Cancer. 2018 Feb 6;118(3):388-397. doi: 10.1038/bjc.2017.432. Epub 2017 Dec 14. Br J Cancer. 2018. PMID: 29241222 Free PMC article.

7

Positive transcription elongation factor b (P-TEFb) is a therapeutic target in human multiple myeloma.

Zhang Y, Zhou L, Leng Y, Dai Y, Orlowski RZ, Grant S. Zhang Y, et al. Oncotarget. 2017 Aug 1;8(35):59476-59491. doi: 10.18632/oncotarget.19761. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938651 Free PMC article.

8

Rational combination strategies to enhance venetoclax activity and overcome resistance in hematologic malignancies.

Grant S. Grant S. Leuk Lymphoma. 2018 Jun;59(6):1292-1299. doi: 10.1080/10428194.2017.1366999. Epub 2017 Aug 24. Leuk Lymphoma. 2018. PMID: 28838268 Free PMC article. Review.

9

Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms.

Nguyen T, Parker R, Hawkins E, Holkova B, Yazbeck V, Kolluri A, Kmieciak M, Rahmani M, Grant S. Nguyen T, et al. Oncotarget. 2017 May 9;8(19):31478-31493. doi: 10.18632/oncotarget.15649. Oncotarget. 2017. PMID: 28416758 Free PMC article.

10

Update on rational targeted therapy in AML.

Shafer D, Grant S. Shafer D, et al. Blood Rev. 2016 Jul;30(4):275-83. doi: 10.1016/j.blre.2016.02.001. Epub 2016 Feb 22. Blood Rev. 2016. PMID: 26972558 Free PMC article. Review.

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