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A novel pipeline for prioritizing cancer type-specific therapeutic vulnerabilities using DepMap identifies PAK2 as a target in head and neck squamous cell carcinomas.
Mol Oncol. 2024 Feb;18(2):336-349. doi: 10.1002/1878-0261.13558. Epub 2023 Dec 13.
Mol Oncol. 2024.
PMID: 37997254
Free PMC article.
HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1α/ERRα axis.
Sannigrahi MK, Rajagopalan P, Lai L, Liu X, Sahu V, Nakagawa H, Jalaly JB, Brody RM, Morgan IM, Windle BE, Wang X, Gimotty PA, Kelly DP, White EA, Basu D.
Sannigrahi MK, et al.
JCI Insight. 2022 Sep 22;7(18):e159600. doi: 10.1172/jci.insight.159600.
JCI Insight. 2022.
PMID: 36134662
Free PMC article.
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