U54 OD020351/OD/NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2016	2
2017	9
2018	7
2019	10
2020	21
2021	13
2022	12
2023	19
2024	4

1

CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa.

Nolan ND, Cui X, Robbings BM, Demirkol A, Pandey K, Wu WH, Hu HF, Jenny LA, Lin CS, Hass DT, Du J, Hurley JB, Tsang SH. Nolan ND, et al. Cell Rep Med. 2024 Apr 16;5(4):101459. doi: 10.1016/j.xcrm.2024.101459. Epub 2024 Mar 21. Cell Rep Med. 2024. PMID: 38518771 Free PMC article.

2

Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia.

Funes S, Jung J, Gadd DH, Mosqueda M, Zhong J, Shankaracharya, Unger M, Stallworth K, Cameron D, Rotunno MS, Dawes P, Fowler-Magaw M, Keagle PJ, McDonough JA, Boopathy S, Sena-Esteves M, Nickerson JA, Lutz C, Skarnes WC, Lim ET, Schafer DP, Massi F, Landers JE, Bosco DA. Funes S, et al. Nat Commun. 2024 Mar 20;15(1):2497. doi: 10.1038/s41467-024-46695-w. Nat Commun. 2024. PMID: 38509062 Free PMC article.

3

Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti-PD-1 Immune Checkpoint Inhibitor Cancer Therapy.

Racine JJ, Bachman JF, Zhang JG, Misherghi A, Khadour R, Kaisar S, Bedard O, Jenkins C, Abbott A, Forte E, Rainer P, Rosenthal N, Sattler S, Serreze DV. Racine JJ, et al. J Immunol. 2024 Apr 15;212(8):1287-1306. doi: 10.4049/jimmunol.2300841. J Immunol. 2024. PMID: 38426910

4

Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy.

Abreo TJ, Thompson EC, Madabushi A, Soh H, Varghese N, Vanoye CG, Springer K, Park KL, Johnson J, Sims S, Ji Z, Chavez AG, Jankovic MJ, Habte B, Zuberi A, Lutz C, Wang Z, Krishnan V, Dudler L, Einsele-Scholz S, Noebels JL, George AL Jr, Maheshwari A, Tzingounis AV, Cooper EC. Abreo TJ, et al. bioRxiv [Preprint]. 2024 Feb 8:2024.01.04.574177. doi: 10.1101/2024.01.04.574177. bioRxiv. 2024. PMID: 38260608 Free PMC article. Preprint.

5

Loss of Endothelial TDP-43 Leads to Blood Brain Barrier Defects in Mouse Models of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Cheemala A, Kimble AL, Tyburski JD, Leclair NK, Zuberi AR, Murphy M, Jellison ER, Reese B, Hu X, Lutz CM, Yan R, Murphy PA. Cheemala A, et al. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571184. doi: 10.1101/2023.12.13.571184. bioRxiv. 2023. PMID: 38168388 Free PMC article. Preprint.

6

Deletion of Vβ3⁺CD4⁺ T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8⁺ T cells.

Ye C, Clements SA, Gu W, Geurts AM, Mathews CE, Serreze DV, Chen YG, Driver JP. Ye C, et al. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2312039120. doi: 10.1073/pnas.2312039120. Epub 2023 Nov 28. Proc Natl Acad Sci U S A. 2023. PMID: 38015847

7

Bypassing pre-existing antibodies extends the applicability of AAV-based retinal therapies.

Hu HF, Tsang SH. Hu HF, et al. Mol Ther. 2023 Dec 6;31(12):3363. doi: 10.1016/j.ymthe.2023.11.005. Epub 2023 Nov 23. Mol Ther. 2023. PMID: 38000369 No abstract available.

8

HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice.

Racine JJ, Misherghi A, Dwyer JR, Maser R, Forte E, Bedard O, Sattler S, Pugliese A, Landry L, Elso C, Nakayama M, Mannering S, Rosenthal N, Serreze DV. Racine JJ, et al. J Immunol. 2023 Dec 15;211(12):1792-1805. doi: 10.4049/jimmunol.2300303. J Immunol. 2023. PMID: 37877672

9

Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons.

Shore AN, Qunies AM, Spitznagel BD, Weaver CD, Emmitte KA, Frankel WN, Weston MC. Shore AN, et al. bioRxiv [Preprint]. 2023 Oct 11:2023.10.11.561953. doi: 10.1101/2023.10.11.561953. bioRxiv. 2023. PMID: 37873369 Free PMC article. Preprint.

10

A novel pathogenic CRB1 variant presenting as Leber Congenital Amaurosis 8 and evaluation of gene editing feasibility.

Sylla MM, Kolesinkova M, da Costa BL, Maumenee IH, Tsang SH, Quinn PMJ. Sylla MM, et al. Doc Ophthalmol. 2023 Dec;147(3):217-224. doi: 10.1007/s10633-023-09951-w. Epub 2023 Oct 7. Doc Ophthalmol. 2023. PMID: 37804373

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