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Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia.
Askarian F, Tsai CM, Cordara G, Zurich RH, Bjånes E, Golten O, Vinther Sørensen H, Kousha A, Meier A, Chikwati E, Bruun JA, Ludviksen JA, Choudhury B, Trieu D, Davis S, Edvardsen PKT, Mollnes TE, Liu GY, Krengel U, Conrad DJ, Vaaje-Kolstad G, Nizet V. Askarian F, et al. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2301538120. doi: 10.1073/pnas.2301538120. Epub 2023 Jul 17. Proc Natl Acad Sci U S A. 2023. PMID: 37459522 Free PMC article.
The Pseudomonas aeruginosa protease LasB directly activates IL-1β.
Sun J, LaRock DL, Skowronski EA, Kimmey JM, Olson J, Jiang Z, O'Donoghue AJ, Nizet V, LaRock CN. Sun J, et al. EBioMedicine. 2020 Oct;60:102984. doi: 10.1016/j.ebiom.2020.102984. Epub 2020 Sep 23. EBioMedicine. 2020. PMID: 32979835 Free PMC article.
48 results