U54 CA090821/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2005	2
2006	4
2007	1
2009	1
2012	1
2024	0

1

Monitoring the development of xenograft triple-negative breast cancer models using diffusion-weighted magnetic resonance imaging.

Stephen RM, Pagel MD, Brown K, Baker AF, Meuillet EJ, Gillies RJ. Stephen RM, et al. Exp Biol Med (Maywood). 2012 Nov;237(11):1273-80. doi: 10.1258/ebm.2012.011326. Exp Biol Med (Maywood). 2012. PMID: 23239438 Free PMC article.

2

Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance.

Ihle NT, Lemos R Jr, Wipf P, Yacoub A, Mitchell C, Siwak D, Mills GB, Dent P, Kirkpatrick DL, Powis G. Ihle NT, et al. Cancer Res. 2009 Jan 1;69(1):143-50. doi: 10.1158/0008-5472.CAN-07-6656. Cancer Res. 2009. PMID: 19117997 Free PMC article.

3

Phase I pharmacokinetic and pharmacodynamic study of 17-N-allylamino-17-demethoxygeldanamycin in pediatric patients with recurrent or refractory solid tumors: a pediatric oncology experimental therapeutics investigators consortium study.

Bagatell R, Gore L, Egorin MJ, Ho R, Heller G, Boucher N, Zuhowski EG, Whitlock JA, Hunger SP, Narendran A, Katzenstein HM, Arceci RJ, Boklan J, Herzog CE, Whitesell L, Ivy SP, Trippett TM. Bagatell R, et al. Clin Cancer Res. 2007 Mar 15;13(6):1783-8. doi: 10.1158/1078-0432.CCR-06-1892. Clin Cancer Res. 2007. PMID: 17363533 Clinical Trial.

4

Redox-sensitive contrast agents for MRI based on reversible binding of thiols to serum albumin.

Raghunand N, Jagadish B, Trouard TP, Galons JP, Gillies RJ, Mash EA. Raghunand N, et al. Magn Reson Med. 2006 Jun;55(6):1272-80. doi: 10.1002/mrm.20904. Magn Reson Med. 2006. PMID: 16700014 Free PMC article.

5

Molecular pharmacology and antitumor activity of palmarumycin-based inhibitors of thioredoxin reductase.

Powis G, Wipf P, Lynch SM, Birmingham A, Kirkpatrick DL. Powis G, et al. Mol Cancer Ther. 2006 Mar;5(3):630-6. doi: 10.1158/1535-7163.MCT-05-0487. Mol Cancer Ther. 2006. PMID: 16546977 Free PMC article.

6

The skin and hair as surrogate tissues for measuring the target effect of inhibitors of phosphoinositide-3-kinase signaling.

Williams R, Baker AF, Ihle NT, Winkler AR, Kirkpatrick L, Powis G. Williams R, et al. Cancer Chemother Pharmacol. 2006 Oct;58(4):444-50. doi: 10.1007/s00280-006-0190-0. Epub 2006 Feb 17. Cancer Chemother Pharmacol. 2006. PMID: 16485116 Free PMC article.

7

The antitumor thioredoxin-1 inhibitor PX-12 (1-methylpropyl 2-imidazolyl disulfide) decreases thioredoxin-1 and VEGF levels in cancer patient plasma.

Baker AF, Dragovich T, Tate WR, Ramanathan RK, Roe D, Hsu CH, Kirkpatrick DL, Powis G. Baker AF, et al. J Lab Clin Med. 2006 Feb;147(2):83-90. doi: 10.1016/j.lab.2005.09.001. J Lab Clin Med. 2006. PMID: 16459166 Free PMC article. Clinical Trial.

8

The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non-small cell lung cancer xenografts.

Ihle NT, Paine-Murrieta G, Berggren MI, Baker A, Tate WR, Wipf P, Abraham RT, Kirkpatrick DL, Powis G. Ihle NT, et al. Mol Cancer Ther. 2005 Sep;4(9):1349-57. doi: 10.1158/1535-7163.MCT-05-0149. Mol Cancer Ther. 2005. PMID: 16170026 Free PMC article.

9

Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478.

Jordan BF, Runquist M, Raghunand N, Baker A, Williams R, Kirkpatrick L, Powis G, Gillies RJ. Jordan BF, et al. Neoplasia. 2005 May;7(5):475-85. doi: 10.1593/neo.04628. Neoplasia. 2005. PMID: 15967100 Free PMC article.

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