U54 AI150472/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

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Subject: U54 AI150472/AI/NIAID NIH HHS/United States[Grant - PubMed

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Year	Number of Results
2017	1
2018	3
2019	13
2020	23
2021	37
2022	22
2023	10
2024	2

105 results

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Kinetic coevolutionary models predict the temporal emergence of HIV-1 resistance mutations under drug selection pressure.

Biswas A, Choudhuri I, Arnold E, Lyumkis D, Haldane A, Levy RM. Biswas A, et al. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2316662121. doi: 10.1073/pnas.2316662121. Epub 2024 Apr 1. Proc Natl Acad Sci U S A. 2024. PMID: 38557187

Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition.

McFadden WM, Casey-Moore MC, Bare GAL, Kirby KA, Wen X, Li G, Wang H, Slack RL, Snyder AA, Lorson ZC, Kaufman IL, Cilento ME, Tedbury PR, Gembicky M, Olson AJ, Torbett BE, Sharpless KB, Sarafianos SG. McFadden WM, et al. Cell Chem Biol. 2024 Mar 21;31(3):477-486.e7. doi: 10.1016/j.chembiol.2024.02.012. Cell Chem Biol. 2024. PMID: 38518746

Elucidating the molecular determinants for binding modes of a third-generation HIV-1 integrase strand transfer inhibitor: Importance of side chain and solvent reorganization.

Sun Q, Biswas A, Lyumkis D, Levy R, Deng N. Sun Q, et al. bioRxiv [Preprint]. 2023 Dec 1:2023.11.29.569269. doi: 10.1101/2023.11.29.569269. bioRxiv. 2023. PMID: 38077045 Free PMC article. Updated. Preprint.

Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.

Gres AT, Kirby KA, McFadden WM, Du H, Liu D, Xu C, Bryer AJ, Perilla JR, Shi J, Aiken C, Fu X, Zhang P, Francis AC, Melikyan GB, Sarafianos SG. Gres AT, et al. Nat Commun. 2023 Sep 12;14(1):5614. doi: 10.1038/s41467-023-41197-7. Nat Commun. 2023. PMID: 37699872 Free PMC article.

Reactive Docking: A Computational Method for High-Throughput Virtual Screenings of Reactive Species.

Bianco G, Holcomb M, Santos-Martins D, Tillack A, Hansel-Harris A, Forli S. Bianco G, et al. J Chem Inf Model. 2023 Sep 11;63(17):5631-5640. doi: 10.1021/acs.jcim.3c00832. Epub 2023 Aug 28. J Chem Inf Model. 2023. PMID: 37639635

Reversible phase separation of ESCRT protein ALIX through tyrosine phosphorylation.

Elias RD, Zhu Y, Su Q, Ghirlando R, Zhang J, Deshmukh L. Elias RD, et al. Sci Adv. 2023 Jul 14;9(28):eadg3913. doi: 10.1126/sciadv.adg3913. Epub 2023 Jul 14. Sci Adv. 2023. PMID: 37450591 Free PMC article.

Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening.

Chopra A, Bauman JD, Ruiz FX, Arnold E. Chopra A, et al. J Med Chem. 2023 May 11;66(9):6013-6024. doi: 10.1021/acs.jmedchem.2c01681. Epub 2023 Apr 28. J Med Chem. 2023. PMID: 37115705 Free PMC article.

Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.

Highland CM, Tan A, Ricaña CL, Briggs JAG, Dick RA. Highland CM, et al. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2220545120. doi: 10.1073/pnas.2220545120. Epub 2023 Apr 24. Proc Natl Acad Sci U S A. 2023. PMID: 37094124 Free PMC article.

Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.

Stacey JCV, Tan A, Lu JM, James LC, Dick RA, Briggs JAG. Stacey JCV, et al. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2220557120. doi: 10.1073/pnas.2220557120. Epub 2023 Apr 11. Proc Natl Acad Sci U S A. 2023. PMID: 37040417 Free PMC article.

ViReMa: a virus recombination mapper of next-generation sequencing data characterizes diverse recombinant viral nucleic acids.

Sotcheff S, Zhou Y, Yeung J, Sun Y, Johnson JE, Torbett BE, Routh AL. Sotcheff S, et al. Gigascience. 2023 Mar 20;12:giad009. doi: 10.1093/gigascience/giad009. Gigascience. 2023. PMID: 36939008 Free PMC article.

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