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Sites of vulnerability in HCV E1E2 identified by comprehensive functional screening.
Pfaff-Kilgore JM, Davidson E, Kadash-Edmondson K, Hernandez M, Rosenberg E, Chambers R, Castelli M, Clementi N, Mancini N, Bailey JR, Crowe JE Jr, Law M, Doranz BJ. Pfaff-Kilgore JM, et al. Cell Rep. 2022 May 24;39(8):110859. doi: 10.1016/j.celrep.2022.110859. Cell Rep. 2022. PMID: 35613596 Free PMC article.
An Antigenically Diverse, Representative Panel of Envelope Glycoproteins for Hepatitis C Virus Vaccine Development.
Salas JH, Urbanowicz RA, Guest JD, Frumento N, Figueroa A, Clark KE, Keck Z, Cowton VM, Cole SJ, Patel AH, Fuerst TR, Drummer HE, Major M, Tarr AW, Ball JK, Law M, Pierce BG, Foung SKH, Bailey JR. Salas JH, et al. Gastroenterology. 2022 Feb;162(2):562-574. doi: 10.1053/j.gastro.2021.10.005. Epub 2021 Oct 13. Gastroenterology. 2022. PMID: 34655573 Free PMC article.
From Structural Studies to HCV Vaccine Design.
Yechezkel I, Law M, Tzarum N. Yechezkel I, et al. Viruses. 2021 May 4;13(5):833. doi: 10.3390/v13050833. Viruses. 2021. PMID: 34064532 Free PMC article. Review.
Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins.
Chen F, Tzarum N, Lin X, Giang E, Velázquez-Moctezuma R, Augestad EH, Nagy K, He L, Hernandez M, Fouch ME, Grinyó A, Chavez D, Doranz BJ, Prentoe J, Stanfield RL, Lanford R, Bukh J, Wilson IA, Zhu J, Law M. Chen F, et al. Immunity. 2021 Apr 13;54(4):781-796.e4. doi: 10.1016/j.immuni.2021.02.013. Epub 2021 Mar 5. Immunity. 2021. PMID: 33675683 Free PMC article.
An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Tzarum N, Giang E, Kadam RU, Chen F, Nagy K, Augestad EH, Velázquez-Moctezuma R, Keck ZY, Hua Y, Stanfield RL, Dreux M, Prentoe J, Foung SKH, Bukh J, Wilson IA, Law M. Tzarum N, et al. Sci Adv. 2020 Jul 24;6(30):eabb5642. doi: 10.1126/sciadv.abb5642. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32754640 Free PMC article.
26 results