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Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge.
Fernández-Romero JA, Abraham CJ, Rodriguez A, Kizima L, Jean-Pierre N, Menon R, Begay O, Seidor S, Ford BE, Gil PI, Peters J, Katz D, Robbiani M, Zydowsky TM. Fernández-Romero JA, et al. Antimicrob Agents Chemother. 2012 Jan;56(1):358-68. doi: 10.1128/AAC.05461-11. Epub 2011 Nov 7. Antimicrob Agents Chemother. 2012. PMID: 22064530 Free PMC article.
An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques.
Kenney J, Aravantinou M, Singer R, Hsu M, Rodriguez A, Kizima L, Abraham CJ, Menon R, Seidor S, Chudolij A, Gettie A, Blanchard J, Lifson JD, Piatak M Jr, Fernández-Romero JA, Zydowsky TM, Robbiani M. Kenney J, et al. PLoS One. 2011 Jan 5;6(1):e15835. doi: 10.1371/journal.pone.0015835. PLoS One. 2011. PMID: 21246052 Free PMC article.