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Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population.
Baguma R, Penn-Nicholson A, Smit E, Erasmus M, Day J, Makhethe L, de Kock M, Hughes EJ, van Rooyen M, Pienaar B, Stone L, Hanekom W, Brennan MJ, Wallis RS, Hatherill M, Scriba TJ. Baguma R, et al. PLoS One. 2017 Sep 8;12(9):e0184563. doi: 10.1371/journal.pone.0184563. eCollection 2017. PLoS One. 2017. PMID: 28886145 Free PMC article.
The Cross-Species Mycobacterial Growth Inhibition Assay (MGIA) Project, 2010-2014.
Brennan MJ, Tanner R, Morris S, Scriba TJ, Achkar JM, Zelmer A, Hokey DA, Izzo A, Sharpe S, Williams A, Penn-Nicholson A, Erasmus M, Stylianou E, Hoft DF, McShane H, Fletcher HA. Brennan MJ, et al. Clin Vaccine Immunol. 2017 Sep 5;24(9):e00142-17. doi: 10.1128/CVI.00142-17. Print 2017 Sep. Clin Vaccine Immunol. 2017. PMID: 28701467 Free PMC article. Review.
Safety and Immunogenicity of the Recombinant BCG Vaccine AERAS-422 in Healthy BCG-naïve Adults: A Randomized, Active-controlled, First-in-human Phase 1 Trial.
Hoft DF, Blazevic A, Selimovic A, Turan A, Tennant J, Abate G, Fulkerson J, Zak DE, Walker R, McClain B, Sadoff J, Scott J, Shepherd B, Ishmukhamedov J, Hokey DA, Dheenadhayalan V, Shankar S, Amon L, Navarro G, Podyminogin R, Aderem A, Barker L, Brennan M, Wallis RS, Gershon AA, Gershon MD, Steinberg S. Hoft DF, et al. EBioMedicine. 2016 May;7:278-86. doi: 10.1016/j.ebiom.2016.04.010. Epub 2016 Apr 19. EBioMedicine. 2016. PMID: 27322481 Free PMC article. Clinical Trial.
Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction.
Chen T, Blanc C, Eder AZ, Prados-Rosales R, Souza AC, Kim RS, Glatman-Freedman A, Joe M, Bai Y, Lowary TL, Tanner R, Brennan MJ, Fletcher HA, McShane H, Casadevall A, Achkar JM. Chen T, et al. J Infect Dis. 2016 Jul 15;214(2):300-10. doi: 10.1093/infdis/jiw141. Epub 2016 Apr 7. J Infect Dis. 2016. PMID: 27056953 Free PMC article.