U01 DK124020/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	5
2022	3
2023	10
2024	0

1

Top-Down Proteomics of Mouse Islets With Beta Cell CPE Deletion Reveals Molecular Details in Prohormone Processing.

Fulcher JM, Swensen AC, Chen YC, Verchere CB, Petyuk VA, Qian WJ. Fulcher JM, et al. Endocrinology. 2023 Nov 2;164(12):bqad160. doi: 10.1210/endocr/bqad160. Endocrinology. 2023. PMID: 37967211 Free PMC article.

2

Highly Reproducible Quantitative Proteomics Analysis of Pancreatic Cancer Cells Reveals Proteome-Level Effects of a Novel Combination Drug Therapy That Induces Cancer Cell Death via Metabolic Remodeling and Activation of the Extrinsic Apoptosis Pathway.

Rasam S, Lin Q, Shen S, Straubinger RM, Qu J. Rasam S, et al. J Proteome Res. 2023 Dec 1;22(12):3780-3792. doi: 10.1021/acs.jproteome.3c00463. Epub 2023 Oct 31. J Proteome Res. 2023. PMID: 37906173

3

Transcriptome and secretome profiling of sensory neurons reveals sex differences in pathways relevant to insulin sensing and insulin secretion.

Moon S, Alsarkhi L, Lin TT, Inoue R, Tahiri A, Colson C, Cai W, Shirakawa J, Qian WJ, Zhao JY, El Ouaamari A. Moon S, et al. FASEB J. 2023 Oct;37(10):e23185. doi: 10.1096/fj.202300941R. FASEB J. 2023. PMID: 37695721

4

Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity.

Nakayasu ES, Bramer LM, Ansong C, Schepmoes AA, Fillmore TL, Gritsenko MA, Clauss TR, Gao Y, Piehowski PD, Stanfill BA, Engel DW, Orton DJ, Moore RJ, Qian WJ, Sechi S, Frohnert BI, Toppari J, Ziegler AG, Lernmark Å, Hagopian W, Akolkar B, Smith RD, Rewers MJ, Webb-Robertson BM, Metz TO; TEDDY Study Group. Nakayasu ES, et al. Cell Rep Med. 2023 Jul 18;4(7):101093. doi: 10.1016/j.xcrm.2023.101093. Epub 2023 Jun 29. Cell Rep Med. 2023. PMID: 37390828 Free PMC article.

5

Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice.

Chen YC, Taylor AJ, Fulcher JM, Swensen AC, Dai XQ, Komba M, Wrightson KLC, Fok K, Patterson AE, Klein Geltink RI, MacDonald PE, Qian WJ, Verchere CB. Chen YC, et al. Diabetes. 2023 Sep 1;72(9):1277-1288. doi: 10.2337/db22-0945. Diabetes. 2023. PMID: 37364047

6

Species-Deconvolved Proteomics for In Situ Investigation of Tumor-Stroma Interactions after Treatment of Pancreatic Cancer Patient-Derived Xenografts with Combined Gemcitabine and Paclitaxel.

Wang X, Niu J, Qian S, Shen S, Straubinger RM, Qu J. Wang X, et al. J Proteome Res. 2023 Jul 7;22(7):2436-2449. doi: 10.1021/acs.jproteome.3c00164. Epub 2023 Jun 13. J Proteome Res. 2023. PMID: 37311110 Free PMC article.

7

Targeted Mass Spectrometry Assays for Specific Quantification of Urinary proPSA Isoforms.

Kitata RB, Hu LY, Lin TT, Nicora CD, Fillmore TL, Nie S, Hudson RD, Liu T, Leach RJ, Liu AY, Qian WJ, Shi T. Kitata RB, et al. J Proteome Res. 2023 Mar 3;22(3):942-950. doi: 10.1021/acs.jproteome.2c00745. Epub 2023 Jan 10. J Proteome Res. 2023. PMID: 36626706 Free PMC article.

8

Highly Accurate and Robust Absolute Quantification of Target Proteins in Formalin-Fixed Paraffin-Embedded (FFPE) Tissues by LC-MS.

Pu J, Xue C, Huo S, Shen Q, Qu Y, Yang X, An B, Angel TE, Chen Z, Mehl JT, Tang H, Yang E, Sikorski TW, Qu J. Pu J, et al. Anal Chem. 2023 Jan 17;95(2):924-934. doi: 10.1021/acs.analchem.2c03473. Epub 2022 Dec 19. Anal Chem. 2023. PMID: 36534410 Free PMC article.

9

High-quality and robust protein quantification in large clinical/pharmaceutical cohorts with IonStar proteomics investigation.

Shen S, Wang X, Zhu X, Rasam S, Ma M, Huo S, Qian S, Zhang M, Qu M, Hu C, Jin L, Tian Y, Sethi S, Poulsen D, Wang J, Tu C, Qu J. Shen S, et al. Nat Protoc. 2023 Mar;18(3):700-731. doi: 10.1038/s41596-022-00780-w. Epub 2022 Dec 9. Nat Protoc. 2023. PMID: 36494494 Free PMC article. Review.

10

Apolipoprotein C3 and circulating mediators of preadipocyte proliferation in states of lipodystrophy.

Brasil BB, Masaji S, Martins BT, Jiang H, Song N, Athena A S, Lucas B, François M, Wei-Jun Q, Rohit KN, Ronald KC. Brasil BB, et al. Mol Metab. 2022 Oct;64:101572. doi: 10.1016/j.molmet.2022.101572. Epub 2022 Aug 11. Mol Metab. 2022. PMID: 35964946 Free PMC article.

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